PRELIM LEC: SOMATIC DEATH Flashcards

1
Q

Refers to the complete cessation of metabolic and functional abilities of an organism

A

SOMATIC DEATH

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2
Q

Occurs 4-6 minutes, then death follows

A

Primary Changes of Death

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3
Q

Primary Changes of Death (CRC)

A
  1. Circulatory failure
  2. Respiratory failure
  3. Central Nervous System failure
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4
Q

start of death when cardiac function
ceases; flat electrocardiogram (ECG), and/or absence of heartbeat is indicative

A

Circulatory failure

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5
Q

decrease O2 and increase CO2; loss of all
processes necessary for life; absence of respiratory sounds and movements is indicative

A

Respiratory failure

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5
Q

loss of coordination and reflexes; absence of brain stem reflex, and/or electroencephalogram (EEG) activity is indicative

A

Central Nervous System failure

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6
Q

Secondary Changes of Death (ARLPDPA)

A
  1. Algor Mortis
  2. Rigor Mortis
  3. Livor Mortis/Sugillation
  4. Post-mortem Clotting

The next 3 stages of death occurs simultaneously and leads to the total digestion of cells:
5. Dessication
6. Putrefaction
7. Autolysis

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7
Q

Cooling of the body; decrease in temperature

A

Algor Mortis

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8
Q

Equalizing of the body temperature to the external temp

A

Algor Mortis

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9
Q

Algor Mortis Normal rate of cooling:

A

7 Fahrenheit/hr

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10
Q

Algor Mortis Sped up by:

A

cold environment, malnutrition/dehydration, severe hemorrhage

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11
Q

Algor Mortis Slowed by:

A

fever, extreme physical activity before death

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12
Q

Stiffening of muscles due to lack of ATP (ATP is
responsible for driving calcium ions back to sarcoplasmic reticulum of muscles)

A

Rigor Mortis

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13
Q

First appears in the involuntary muscles of heart

A

Rigor Mortis

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14
Q

Observed in eyelids, followed by neck, then lower extremities

A

Rigor Mortis

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14
Q

Starts 2-3 hrs post-mortem, completes 6-12 hrs post-mortem; persists for 3-4 days

A

Rigor Mortis

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15
Q

After 3 to 4 days, relaxation occurs due to breakdown of contracted muscles

A

Rigor Mortis

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16
Q

Rigor Mortis Factors:

A

muscle activity by the time of death;

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16
Q

Rigor Mortis Sped up by:

A

warm environment; infancy; thin-layered muscles

16
Q

Rigor Mortis Slowed by:

A

cold environment; obese people

17
Q

Purplish discoloration of skin due to blood stasis

A

Livor Mortis/Sugillation

18
Q

Blood vessels dilate due to loss of muscle tone

A

Livor Mortis/Sugillation

18
Q

Lividity of the dependent portions of the body due to settling of blood to the lowest parts of the body at the time of death

A

Livor Mortis/Sugillation

19
Q

Cause

Livor Mortis/Sugillation

A

Post-mortem stasis of blood

20
After application of pressure (Blanching test) | Livor Mortis/Sugillation
Discoloration disappears
21
After incision | Livor Mortis/Sugillation
Has oozing
22
Cause | Ecchymosis
Trauma
23
After application of pressure (Blanching test) | Ecchymosis
No disappearance
24
After incision | Ecchymosis
No oozing
25
Occurs immediately after death; apparent only in autopsy
Post-mortem Clotting
26
Appearance | Post-mortem Clotting
Upper layer is clear (resembles chicken fat); RBC settles at the lowest part of the blood vessel (resembles currant jelly)
26
Consistency | Post-mortem Clotting
Rubbery
27
Shape | Post-mortem Clotting
Assumes blood vessel shape
28
Appearance | Ante-Mortem Clot
Has tangled, irregular fibrin
29
Shape | Ante-Mortem Clot
Seldom assumes blood vessel shape
30
Consistency | Ante-Mortem Clot
Non-rubbery
30
General drying and wrinkling of fluid-filled organs;
Dessication
30
most evident in the cornea, and anterior chamber of eye
Dessication
31
Decomposition of body carried out by microbial action (normal flora from gut migrates to blood vessels and spreads all over the body)
Putrefaction
32
Putrefaction Principal agent:
*Clostridium welchii* (gram-positive, anaerobic, rod-shaped)
33
Putrefaction First external sign:
Greenish discoloration of skin over the right iliac fossa due to bacterial hydrogen sulfide reacting with hemoglobin, thus forming sulphahemoglobin which stains the area green
34
Eventual production of foul-smelling gas due to invasion of saprophytes, which leads to distension of abdomen, swelling of face and genitalia, and liquefaction of internal organs
Putrefaction
35
Most resistant to putrefaction: prostate gland
Putrefaction
36
“Self-destruction”; the self-digestion of the cells by their own enzymes;
Autolysis
37
First external sign is the whitish appearance of cornea
Autolysis
38
The next 3 stages of death occurs simultaneously and leads to the total digestion of cells:
1. Dessication 2. Putrefaction 3. Autolysis