Pregnancy Physiological Changes Flashcards
Changes in pregnancy for Co
SV
hR
Increases by 40%
SV increases by 30 %
HR increase by 20%
Cardiac output increasement in pregnancy is
1.5 L
From 4.5 L to 6 L /min
Plateaus of cardiac output increase en is reached at which gestational age
It’s reached at 24-30 weeks GA
PVR changes in pregnancy
Decreases by 5%
Blood pressure changes in pregnancy
Decreases by 10%
Is pregnancy associated with vasodilation or vasoconstriction
Vasodilation due to progesterone effect
Distribution of CO in pregnancy
Highest to
Kidney uterus skin GI/ breast
Highest to skin 500ml/ min
Uterus 400ml/min
Kif]dney 300ml/min
Hibreast 300 ml/min
What is the increase in cardiac output durin labor
It increased by 2 L/min
ECG changes in pregnancy
Ventricles
Axis deviation
Heart apex site,
T wave
Q wave
St
Left ventricular hypertrophy and dilatation
Left axis deviation by 15%
Apex is shifted anterior ly and to the left
T wave inverted Qlead 3
Q wave in lead 3 an avF
Nonspecific changes in st
Hematological changes in pregnancy
Plasma volume
RBCS
WBCs
Clotting factors
Type of anemia
Hematocrit
Plasma volume increases by 50% from 2600ml to 3800 ml no further increase after 32 weeks
RBCS total volume increas by 18% 1400ml 1650 ml
Wbcs increasing
Piloting factors increases
Hemodilutuonal anemia - physiological anemia occurs
Hematocrit decreases .
Endothelial changes in pregnancy
Vasodilation
Pro coagulant status
Vasodilation during pregnancy occurs due to 4 factors
1 ) mainly progesterone
2 ) increase No nitrous oxide
3) increase prostacyclin pGI2
Decreased ADMa asymmetrical dimethylarginine
Pureperium diuresis clotting factors
Diuresis increased first 48 hours after delivery
Clotting factors remain high .
Special senses changes in pregnancy
Corneal edema
Change in smell
Chengee in taste
