Pregnancy and Pharmacology Flashcards
1
Q
Effect of warfarin on prenancy?
A
10-20% of babies exposed are affected.
Facial and bony deformities.
Foetal haemorrhage.
Blindness.
Stillbirth.
2
Q
What is sodium Valproate?
A
Common anti-epileptic medication
3
Q
Effects of sodium valproate on pregnancy?
A
If used in pregnancy can cause neural tube defects, skeletal defects, hypospadias and heart defects.
Effects appear to persist and manifest as a range of neuro-developmental abnormalities and autism spectrum disorders.
4
Q
Which medication do not cross the placenta?
A
LMWH, insulin
