Pregnancy and N/V

Question 1

What are risk factors for GN/V

Answer 1

1. young age
2. first pregnancy
3. obesity
4. family hx

Question 2

What are non pharm tx for N/V in pregnancy?

Answer 2

1. smaller more frequent meals
2. avoid spice/odor
3. decrease stress/ long working hours
4. start prenatal vitamins 3 months prior to pregnancy

Question 3

What are pharm treatments for GN/V ?

Answer 3

pyridoxine (vit B6) +/- doxylamine (antihistamine)

Question 4

What are SEs with pyridoxine (vit B6) + doxylamine (antihistamine)

Answer 4

1. drowsiness
2. anticholinergic effects (dry mouth, constipation)
3. caution with increased intraocular pressure and narrow angle glaucoma

Question 5

What are s/s of hyperemesis gravidarum?

Answer 5

1. weight loss >5% initial body weight
2. electrolyte imbalance (hypokalemia)
3. ketonuria
4. dehydration

Question 6

What is treatment of hyperemesis gravidarum?

Answer 6

1. dextrose with thiamine
2. Methylprednisolone (> 10 weeks gestation)
3. acupunture/ hypnosis