Pregnancy Flashcards
What secretion from the anterior pituitary is greatest during ovulation
- LH
- luteinizing hormone
What hormone does the follicles produce?
- oestradiol
What is the corpus luteum?
- mass of cells that forms in the ovary, prior to fertilisation
What hormone does the corpus luteum produce?
- progesterone
What hormone does the implanted fertilised embryo produce?
- HCG
- human chorionic gonadotropin
Pregnancy tests measure which hormone?
- HCG
What hormones does the placenta produce?
- human placental lactogen
- placental progesterone
- placental oestrogens
What hormone does the anterior pituitary gland produce towards the end of pregnancy?
- prolactin
If no implantation occurs of a fertilised embryo what happens to the levels of progesterone?
- progesterone levels fall
What 2 hormones cause insulin resistance in mothers?
- progesterone
- HPL
What week does fetal organogenesis occur?
- start of week 5 or earlier
Complications of diabetes in pregnancy?
- congenital malformation
- prematurity
- intra-uterine growth retardation
- macrosomia
What are the complications of gestational diabetes?
- macrosomia
- polyhydramnios
- intrauterine death
- hypoglycaemia of new born
What is macrosomia?
- big baby
- > 90th percentile
- birth weight >4kg
What dose of folic acid should be given to women with diabetes hoping to have a child?
- folic acid 5mg
- 3 months prior to pregnancy
What medications should be avoided in a diabetic pregnancy?
- ACEI
- Statins
What dosage of aspirin should be started in a diabetic pregnancy?
- 150mg
- at 12 weeks
What is the target BG before a meal in a diabetic pregnancy?
<4-5.5mmol/l
What is the target BG 2hrs after a meal in a diabetic pregnancy?
<6-6.5mmol/l
T2DM patient during pregnancy may have what medication swapped?
- metformin swapped for insulin??
In a women with gestational diabetes what risks are there post-delivery?
- T1DM/T2DM later in life (50%)
- fasting BG 6 weeks post-delivery
During pregnancy there is an increased demand for thyroxine?
TRUE OR FALSE
- TRUE
Hypothyroidism and hyperthyroidism has what risks for pregnancy?
- reduced fertility
- still birth
- thyroid crisis in labour
- transient neonatal thyrotoxicosis
What drug treatment should be given for hypothyroidism in pregnancy?
- increase thyroxine by 25mcg as soon as pregnant
