Obesity/bone health Flashcards
1
Q
What is the importance of remodelling units of bone?
A
- contributes to calcium homeostasis and skeletal repair
2
Q
What are osteoclasts?
A
- multi nucleated
- responsible for bone resorption
- breakdown bone
3
Q
What are osteoblasts?
A
- mononuclear cells
- responsible for bone formation
4
Q
What are osteocytes
A
- primary cell of mature bone
- derived from osteoblasts
- sense mechanical strain
5
Q
There is a decrease in trabecular thickness as we age?
TRUE OR FALSE
A
- true
6
Q
Define osteoporosis?
A
- progressive systemic skeletal disease
- low bone mass
- increase in bone fragility and susceptibility to fracture
7
Q
Common sites of fractures?
A
- neck of femur
- vertebral body
- distal radius
- humeral head
8
Q
When should someone be referred for a DXA scan?
A
- when their 10year risk assessment is at least 10%
9
Q
Osteopenia is defined as?
A
- BMD >1 SD below mean
10
Q
Osteoporosis is defined as?
A
- BMD > 2.5 SD below mean
11
Q
The lower the T score___
A
- the greater the fracture risk
12
Q
Name some endocrine secondary causes of bone thinning?
A
- hyperthyroidism
- hyperparathyroidism
- cushing’s
13
Q
What is the minimum recommended calcium intake?
A
- 700mg
14
Q
Drug treatment for osteoporosis?
A
- calcium and vitamin D supplements
- bisphosphonates
15
Q
What is the first line drug for osteoporosis?
A
- bisphosphonates
