Hormones Flashcards
1
Q
What are the 3 subtypes of hormones?
A
- peptide hormones
- amino acid derived
- steroid hormones
2
Q
Explain GPCR
A
o Extracellular, transmembrane, intracellular
o Protein structure than spans the membrane 7 times
o Activation of intracellular cascades
o G protein – alpha, beta, gamma subunits
3
Q
Example of a Receptor tyrosine kinase
A
- insulin receptor
4
Q
Example of a Receptors associated with tyrosine kinase activity
A
- growth hormone reception
5
Q
Raised thyroid?
A
- hypothyroid
6
Q
Suppressed thyroid?
A
- hyperthyroid
7
Q
Assessing pituitary function?
A
- 9am cortisol
- FT4, FT3, TSH
- Prolactin
8
Q
Hypothalamic-pituitary adrenal axis is _____ feedback
A
negative feedback
9
Q
Cortisol secretion is ____
A
- circadian
- changes with time of day
10
Q
Testosterone should be measured at what time?
A
- 9am
11
Q
What is prolactin secreted by?
A
- anterior pituitary
12
Q
Hormone excess what test?
A
- suppression test
13
Q
Hormone deficiency what test?
A
- stimulation test
14
Q
Addison’s disease?
A
- adrenal insufficiency
15
Q
Cushing’s syndrome?
A
- Cortisol excess
16
Q
ACTH dependant Cushings?
A
- pituitary
17
Q
ACTH independant Cushings?
A
- adrenal
