Hormones Flashcards

1
Q

What are the 3 subtypes of hormones?

A
  • peptide hormones
  • amino acid derived
  • steroid hormones
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2
Q

Explain GPCR

A

o Extracellular, transmembrane, intracellular
o Protein structure than spans the membrane 7 times
o Activation of intracellular cascades
o G protein – alpha, beta, gamma subunits

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3
Q

Example of a Receptor tyrosine kinase

A
  • insulin receptor
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4
Q

Example of a Receptors associated with tyrosine kinase activity

A
  • growth hormone reception
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5
Q

Raised thyroid?

A
  • hypothyroid
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6
Q

Suppressed thyroid?

A
  • hyperthyroid
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7
Q

Assessing pituitary function?

A
  • 9am cortisol
  • FT4, FT3, TSH
  • Prolactin
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8
Q

Hypothalamic-pituitary adrenal axis is _____ feedback

A

negative feedback

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9
Q

Cortisol secretion is ____

A
  • circadian

- changes with time of day

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10
Q

Testosterone should be measured at what time?

A
  • 9am
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11
Q

What is prolactin secreted by?

A
  • anterior pituitary
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12
Q

Hormone excess what test?

A
  • suppression test
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13
Q

Hormone deficiency what test?

A
  • stimulation test
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14
Q

Addison’s disease?

A
  • adrenal insufficiency
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15
Q

Cushing’s syndrome?

A
  • Cortisol excess
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16
Q

ACTH dependant Cushings?

A
  • pituitary
17
Q

ACTH independant Cushings?

A
  • adrenal