Pre anesthetic drugs Flashcards
why are pre anesthetic drugs administered? (3)
- Facilitate handling of the patient
- Decrease undesirable side effects of general anesthetics
- Provide analgesia during surgical procedures
what are the categories of the pre anesthetic drugs? (3)
- anticholinergic
- sedatives and tranquilizers
- non steroidal anti inflammatories (NSAIDs)
what are the anticholinergic drugs? (2)
- atropine
2. glycopyrrolate
which anticholinergic is an older drug?
atropine
which anticholinergic is derived from deadly night shade plant?
atropine
which species do NOT get atropine?
w
rabbits
how do anticholinergics work?
block the effect of teh parasympathetic nervous system
which anticholinergic is newer and synthetiic?
glycopyrrolate
which anticholinergic has a longer lasting effect?
glycopyrrolate
which anticholinergic is less likely to cross the placental barrier?
anticholinergic
mydriasis is…
dilation of the pupils
what are the effects of anticholinergics? (5)
- prevent abnormally slow HR
- prevent excessive salivation and repiratory secretions
- can decrease GI motility
- can cause mydriasis
- can cause bronchodilation
what is the purpose for administering tranquilizers/sedatives? (4)
- decrease fear and apprehension
- decrease the need for more anesthetic induction/maintenance
- decrease pain and discomfort post op
- facilitate induction and recovery
what are some commonly used tranquilizers/sedatives? (4)
- phenothiazine
- denzodiazipines
- alpha 2 agonist
- opioids
what are some examples of phenothiazines? (2)
- acepromazine
2. chorpromazine
what are the effects of phenothiazines? (6)
- CNS depression
- antiemetic
- antiarrhythmic
- peripheral vasodilation
- may lower seizure threshold
- antihistaminic effect
what does an antiemetic do?
prevents vomiting
what does an antiarrhythmic do?
supresses abnormal rhythms
what can peripheral dialation lead to?
excessive heat loss
phenothiazapines DO NOT provide…
analgesia
what considerations in animals are more sensitive to phenothiazine effects? (2)
- older dogs
2. large breeds
what can phenothiazines cause in stalions?
penile prolapse
where are phenothiazines metabolized?
liver
how long are the effects of phenothiazines?
4 - 8 hours