Pre anesthetic drugs Flashcards

1
Q

why are pre anesthetic drugs administered? (3)

A
  1. Facilitate handling of the patient
  2. Decrease undesirable side effects of general anesthetics
  3. Provide analgesia during surgical procedures
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2
Q

what are the categories of the pre anesthetic drugs? (3)

A
  1. anticholinergic
  2. sedatives and tranquilizers
  3. non steroidal anti inflammatories (NSAIDs)
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3
Q

what are the anticholinergic drugs? (2)

A
  1. atropine

2. glycopyrrolate

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4
Q

which anticholinergic is an older drug?

A

atropine

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5
Q

which anticholinergic is derived from deadly night shade plant?

A

atropine

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6
Q

which species do NOT get atropine?

w

A

rabbits

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7
Q

how do anticholinergics work?

A

block the effect of teh parasympathetic nervous system

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8
Q

which anticholinergic is newer and synthetiic?

A

glycopyrrolate

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9
Q

which anticholinergic has a longer lasting effect?

A

glycopyrrolate

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10
Q

which anticholinergic is less likely to cross the placental barrier?

A

anticholinergic

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11
Q

mydriasis is…

A

dilation of the pupils

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12
Q

what are the effects of anticholinergics? (5)

A
  1. prevent abnormally slow HR
  2. prevent excessive salivation and repiratory secretions
  3. can decrease GI motility
  4. can cause mydriasis
  5. can cause bronchodilation
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13
Q

what is the purpose for administering tranquilizers/sedatives? (4)

A
  1. decrease fear and apprehension
  2. decrease the need for more anesthetic induction/maintenance
  3. decrease pain and discomfort post op
  4. facilitate induction and recovery
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14
Q

what are some commonly used tranquilizers/sedatives? (4)

A
  1. phenothiazine
  2. denzodiazipines
  3. alpha 2 agonist
  4. opioids
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15
Q

what are some examples of phenothiazines? (2)

A
  1. acepromazine

2. chorpromazine

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16
Q

what are the effects of phenothiazines? (6)

A
  1. CNS depression
  2. antiemetic
  3. antiarrhythmic
  4. peripheral vasodilation
  5. may lower seizure threshold
  6. antihistaminic effect
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17
Q

what does an antiemetic do?

A

prevents vomiting

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18
Q

what does an antiarrhythmic do?

A

supresses abnormal rhythms

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19
Q

what can peripheral dialation lead to?

A

excessive heat loss

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20
Q

phenothiazapines DO NOT provide…

A

analgesia

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21
Q

what considerations in animals are more sensitive to phenothiazine effects? (2)

A
  1. older dogs

2. large breeds

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22
Q

what can phenothiazines cause in stalions?

A

penile prolapse

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23
Q

where are phenothiazines metabolized?

A

liver

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24
Q

how long are the effects of phenothiazines?

A

4 - 8 hours

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25
what are some benzodiazepams? (4)
1. diazepam 2. midazolam 3. zolazepam 4. alprazolam
26
what is an anticonvulsant?
antiseizure medication
27
which sedative/tranquilizer may animals not respond to or become excited on?
phenothiazine
28
what schedule of control are benzodiazepams?
schedule IV
29
this benzodiazepams has a short duration?
diazepam
30
which drug can diazepam be mixed with?
ketamine
31
why is diazepam NOT compatible with other drugs?
solution is not water soluble
32
how is diazepam administered?
IV only, give slowly
33
what can diazepam be used for with cats?(2)
1. appetite stimulate | 2. relieve anxiety
34
how are benzodiazepams metabolized by cats?
slowly, by the liver
35
how are benzodiazepams metabolized by dogs?
fast, by the liver
36
how can the effects of benzodiazepams be reversed?
antagonist flumazenil
37
what is special about midazolam?
water soluble and can be mized with other durgs IM
38
what are some examples of alpha 2 agonist (3)
1. zylazine 2. detomidine 3. dexmedetomidine
39
which agonist is not used most ofte? | why?
xylazine | will make cats vomit
40
when would you not want to use alpha 2 agonists?
if cardiovascular system is impaired
41
what can the labled dose of alpha 2 agonist cause
pre anesthetic depression
42
what kind of large animals are sensitive to alpha 2 agonists?
ruminants
43
where are alpha 2 agonist metabolized?
liver
44
what are the alpha 2 antagonist?
1. yobine | 2. antisedan
45
what tranquilized may panting be observed?
opioids (normal response)
46
what are some opiods? (7)
1. morphine 2. fentanyl 3. hydromorphone 4. oxymorphone 5. meperedine 6. buprenorphine 7. butorphenol
47
what are the effects of opiods? (4)
1. CNS depression 2. analgesia 3. vomiting and defecating followed by constipation 4. respiratory depression at high doses
48
neuroleptanalgesia is...
opioids mixed with another tranquilizer/sedtive to provide better sedation
49
what noises do animal respond to with opioids?
loud metalic noise
50
which tranquilizer/sedative will have a slow onset with long duration?
phenothiazine
51
which opioid can cause malignant hypothermia?
hydromorphone
52
which species tent to react to opiods?
cats
53
which opioids are the best for cats? (3)
1. fentanyl 2. bupe 3. butorphanol
54
what is the purpose of NSAIDs as a preanesthetic drug?
provides pain relief during sugical procedure
55
what are some commonly used NSAIDs? (2)
1. carprofen - rimadyl | 2. meloxicam - metacam
56
what are the concerns with using an NSAID as a pre anesthetic? (2)
1. toxic to kidney due to blood pressure | 2. interfere with prostaglandin that helps control blood pressure
57
what are the effects of alpha 2 agonist? (6)
1. CNS depression 2. muscle relaxation 3. analgesia 4. CV depression 5. respiratory depression 6. vomiting
58
what are the effects of the benzodiazepams?
1. CNS depression 2. anticonvulsant 3. muscle relaxant
59
which sedative/tranquilizer can be used as an anticonvulsant?
benzodiazepam
60
which sedative/tranquilizer can be a muscle relaxant?
1. benzodiazepam | 2. alpha 2 agonist
61
which sedative/tranquilizer is an analgesic?
1. opioids | 2. alpha 2 agonist
62
which sedative/tranquilizer can cause vomiting and deficating followed by constipation?
opioids
63
which sedative/tranquilizer can cause resp. depression at high doses?
opiods
64
which sedative/tranquilizer can cause respiratory and CV depression?
alpha 2 agonist
65
which sedative/tranquilizer can be used as an antiemetic?
phenothiazines
66
which sedative/tranquilizer can be an antiarrhythmic?
phenothiazines
67
which sedative/tranquilizer can cause peripheral vasodilation?
phenothiazines
68
which sedative/tranquilizer can lower seizure threshold?
phenothiazines
69
which sedative/tranquilizer can have an antihistaminic effect?
phenothiazines