local anesthesia Flashcards
local anesthsia is…
loss of pain sensation and movement in an area of the body due to blockage of nerve conduction
how does local anesthisia work?
interferes with movement of sodium ions across neuronal cell membranes
when is local anesthesia used?
Minor surgical procedures that don’t require
general anesthetic
what is important when considering local anestheisa?
Animals temperament
what does local anesthetics interfere in the body?
transmission of nerve impulse along nerve fibers
what are the two groups of local anesthetic dugs?
- esters
2. amides
what are some examples of esters? (4)
- Cocaine
- Procaine
- Chlorprocaine
- Proparacaine
how are esters metabolized?
rapidly metabolized by enzyme in blood
which group of local anesthetics are not popular in veterinary medicine?
esters
which ester is used in opthalmic solution?
Tetracaine (proparacain)
how long are the effects of esters?
short duration
what are some examples of amides?
- Lidocaine
- Mepivacaine
- Bupivacaine
where are amides metabolized?
liver
which amide is more popular?
lidocaine
which ester is lidocain 2x more potent then?
procaine
how quick is the onset of lidocain?
rapid
how long are the effects of lidocain?
1 ½ - 2 hrs.
what can lidocain be used to help treat?
dysrhythmias (w/o epi)
which amide is commonly used for horse nerve block?
Mepivacaine
which amide is mepivacain less irritating than?
lidocain
how quick is the onset of mepivacain?
rapid
how long is the effect of mepivacain?
1 ½-3 hrs.
how potent is mepivacain?
2 ½ X’s as potent
which amide is used for prolonged analgesia?
Bupivacaine