local anesthesia Flashcards

1
Q

local anesthsia is…

A

loss of pain sensation and movement in an area of the body due to blockage of nerve conduction

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2
Q

how does local anesthisia work?

A

interferes with movement of sodium ions across neuronal cell membranes

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3
Q

when is local anesthesia used?

A

Minor surgical procedures that don’t require

general anesthetic

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4
Q

what is important when considering local anestheisa?

A

Animals temperament

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5
Q

what does local anesthetics interfere in the body?

A

transmission of nerve impulse along nerve fibers

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6
Q

what are the two groups of local anesthetic dugs?

A
  1. esters

2. amides

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7
Q

what are some examples of esters? (4)

A
  1. Cocaine
  2. Procaine
  3. Chlorprocaine
  4. Proparacaine
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8
Q

how are esters metabolized?

A

rapidly metabolized by enzyme in blood

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9
Q

which group of local anesthetics are not popular in veterinary medicine?

A

esters

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10
Q

which ester is used in opthalmic solution?

A

Tetracaine (proparacain)

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11
Q

how long are the effects of esters?

A

short duration

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12
Q

what are some examples of amides?

A
  1. Lidocaine
  2. Mepivacaine
  3. Bupivacaine
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13
Q

where are amides metabolized?

A

liver

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14
Q

which amide is more popular?

A

lidocaine

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15
Q

which ester is lidocain 2x more potent then?

A

procaine

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16
Q

how quick is the onset of lidocain?

17
Q

how long are the effects of lidocain?

A

1 ½ - 2 hrs.

18
Q

what can lidocain be used to help treat?

A

dysrhythmias (w/o epi)

19
Q

which amide is commonly used for horse nerve block?

A

Mepivacaine

20
Q

which amide is mepivacain less irritating than?

21
Q

how quick is the onset of mepivacain?

22
Q

how long is the effect of mepivacain?

A

1 ½-3 hrs.

23
Q

how potent is mepivacain?

A

2 ½ X’s as potent

24
Q

which amide is used for prolonged analgesia?

A

Bupivacaine

25
how potent is bupivacain over procain?
8-10 times more potet
26
how quick is the onset of bupivacain?
slow (15-30 minutes)
27
how long are the effects of bupivacain?
4-6 hours
28
what are some adverse effects of local anesthetics?
1. Tissue irritation 2. Allergic reaction 3. Nerve trauma 4. Respiratory paralysis, sympathetic blockade w/ epidural injecitons 5. Systemic toxicity
29
what nerve trauma can happen with local anesthetics?
temporary or permanent loss of function
30
what signs can be seen with a sympathetic blockade caused by local anesthetics ?
decreased HR, BP, CO
31
what signs are seen with systemic toxcity caused by overdose of local anesthetics?
1. muscle twitching 2. sedation or hyperexcitability 3. convulsions 4. respiratory depression
32
which species are most sensitive to lidocain? (3)
Goats, sheep, and cat
33
what is the toxic dose of lidocain in cats?
8-10 mg/kg
34
what are the specific techniques for localized anesthesia? (3)
1. topical 2. Localized infiltration 3. Regional injection
35
what are the types of localized infiltration?
1. Line block | 2. Nerve block
36
what are the types of regional injection?
1. epidural block | 2. Paravertebral block