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Biochem Test II > Powerpoints > Flashcards

Powerpoints Flashcards

1
Q

What is hereditary fructose intolerance caused by?

A

aldolase B

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2
Q

What intermediate in glycolysis will be passed in the presence of arsenate?

A

13bPG

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3
Q

Where does hexokinase convert fructose to F6P?

A

muscle

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4
Q

Where does fructokinase convert fructose into F1P?

A

liver

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5
Q

What is the function of aldolase B?

A

convert F1P into glyceraldehyde

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6
Q

What is the definition of galactosemia?

A

failure to use galactose in glycolysis

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7
Q

Newborns presenting with galactosemia present with what?

A

milk intolerance and signs of liver failure

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8
Q

What is the main regulated step of glycolysis?

A

PFK I

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9
Q

Where is the glycerol phosphate shuttle located?

A

brain and muscle

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10
Q

Where is the malate-aspartate shuttle located?

A

liver and heart

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11
Q

Can the body synthesize glucose from fat?

A

No

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12
Q

What does acetyl-CoA do in relation to carbohydrate metabolism?

A

inhibits PDH

activates pyruvate carboxylase

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13
Q

What are the products of the non-oxidative phase of the pentose phosphate pathway?

A

F6P and GA3P

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14
Q

What drug are patients with G6P dehydrogenase inactivity sensitive to? and what food?

A

primaquine and fava beans

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15
Q

Thiamine affects what type of reactions of the PPP?

A

transketolase reactions

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16
Q

What activated sugar does UDP-glucose pyrophosphorylase act on?

A

G1P

17
Q

Where are proteoglycans degraded?

A

lysosomes

18
Q

What are the most abundant saccharides attached to proteins?

A

mannose, glucose and fucose

19
Q

What are two hallmarks of defective FA uptake?

A

hypoglycemia and low ketone body synthesis

20
Q

How many ATP can an acetyl-CoA molecule yield?

A

10 each

21
Q

Palmitic acid yields?

A

10 acetyl-CoA

7 NADH and FADH2

22
Q

What are two hallmarks of peroxisomal beta-oxidation?

A

preferentially degrade long chain FAs and produce H2O2

23
Q

What enzyme deficiency sometimes causes acute fatty liver of pregnancy?

A

LCHAD

24
Q

What else can cause AFLP?

A

fetus releasing hydroxyacyl metabolites

25
Q

Where is phytanic acid found?

A

chlorophyl

26
Q

What is beta-hydroxybutyrate oxidized to?

A

acetoacetate

27
Q

What is the function of acetoacetate:succinyl-CoA transferase?

A

catalyze formation of acetoacetyl-CoA OUTSIDE of the liver

28
Q

What is the function of FA synthase?

A

palmitic acid

29
Q

What is the function of glycerol phosphate dehydrogenase?

A

to synthesize glycerol-3-phosphate from DHAP

30
Q

What metabolic intermediate activates FA synthase?

A

citrate

31
Q

What leaflet does arachidonic acid occupy?

A

inner

32
Q

What are leukotrienes synthesized from?

A

arachidonic acid

33
Q

What amino acid is contained in leukotrienes?

A

cysteine

34
Q

What is the backbone of plasmalogen?

A

DHAP

Biochem Test II (14 decks)

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