Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biochem Test II > Carbs IV > Flashcards

Carbs IV Flashcards

1
Q

Where is glycogen synthesis performed?

A

muscle and liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the difference between storage location of glycogen?

A

muscle = stores only for muscle

liver = stores for entire body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the function of UDP-glucose pyrophosphorylase?

A

to form UDP-glucose from UTP and G1P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the function of phosphoglucomutase?

A

G6P to G1P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Glycogen phosphorylase releases glucose molecules from glycogen in what form?

A

G1P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Is de-branching enzyme efficient?

A

one glucose is lost as G1P due to alpha-glucosidase activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What product inhibits the activity of hexokinase?

A

G6P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the difference between muscle and liver in response to glucagon stimulation?

A

muscles do not possess glucagon receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What other property of muscles contributes to their inability to respond to glucagon?

A

muscles do not possess glucose-6-phosphatase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the difference between muscle and liver and their glycogenolysis reactions in response to epinephrine?

A

epinephrine causes the liver the breakdown glycogen

epinephrine causes the muscle to breakdown glycogen and to also increase glycolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the effetcs of PKA on glycogen synthase?

A

glycogen synthase is inactivated by PKA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do patients with a glycogen storage disease usually present with?

A

muscle weakness/exercise intolerance

enlarged liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What defect is present in Van Gierke Disease? (type I)

A

defect in glucose-6-phosphatase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What defect is present in Pompe Disease? (type II)

A

alpha-glucosidase deficiency

lysosomes fill with glycogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What defect is present in Cori diease? (type III)

A

glycogen debranching enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What defect is present in McArdle? (type V)

A

glycogen phosphorylase

17
Q

What can MEOS do other than oxidize alcohol?

A

oxidize NADPH

18
Q

What does heavy alcohol consumption induce?

A

MEOS

19
Q

When NADH is high, what two metabolic intermediates disappear?

A

pyruvate and OAA

20
Q

What two enzymes contribute to the disappearance of pyruvate and OAA?

A

lactate dehydrogenase and malate dehydrogenase

21
Q

In general, what two major metabolic pathways are inhibited by NADH?

A

citric acid cycle and gluconeogenesis

22
Q

What enzyme converts G1P into UDP-glucose?

A

UDP-glucose-pyrophosphorylase

23
Q

Are hexokinase and glucokinase stimulated or inhibited by insulin?

A

both are stimulated

24
Q

What is the difference in phosphorylation states between glycogen phosphorylase and glycogen synthase?

A

synthase = active when de-phosphorylated

phosphorylase = active when phosphorylated

25
Q

What induces MEOS?

A

heavy alcohol consumption

26
Q

What two constituents of the CAC disappear during heavy alcohol consumption when NADH is high?

A

OAA and pyruvate

Biochem Test II (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions