Carb I Flashcards

1
Q

How many days does hemoglobin last in circulation?

A

120 days

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2
Q

How is glucose converted to gluconolactone?

A

oxidation of the C1 carbon

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3
Q

What is formed if hexose is oxidized at its C6 carbon?

A

uronic acids

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4
Q

What can happen to glucose is blood glucose levels are too high?

A

glucose is directly reduced to sorbitol

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5
Q

What is N-acetyl-glucosamine formed from?

A

fructose-6-phosphate

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6
Q

Sulfotransferase can add sulfate groups to what carbons?

A

C6, C4 or C2

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7
Q

What amino acids is aspartame broken down into?

A

phenylalanine and aspartic acid

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8
Q

glycogen synthase transfers a glucose from what molecule to an existing chain of glycogen?

A

UDP glucose

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9
Q

What is the function of UDP glucoronyltransferases?

A

to transfer glucoronic acid from UDP glucoronate to a variety of non-specific substrates (most importantly bilirubin)

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10
Q

How do glycosyltransferases aid to bacteria and fungi?

A

Aid in the development of their cell wall

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11
Q

What contributes to the maltose dimer?

A

glucose - glucose

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12
Q

what contributes to the lactose dimer?

A

galactose - glucose

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13
Q

sucrose dimer?

A

glucose - fructose

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14
Q

What type of bond connects glycogen and starch?

A

alpha 1-4 linkages

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15
Q

What type of connections does glycogen contain?

A

alpha 1-4 and alpha 1-6

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16
Q

What types of linkages do plants and fungi employ to link their sugar polymers? Can humans digest these?

17
Q

What are the substituents of starch?

A

amylose and amylopectin

18
Q

What linkages are featured in glycosaminoglycans?

A

beta 1-6 and beta 1 - 4

alpha 1-4

19
Q

Starch and glycogen digestion begins with what enzyme?

A

alpha-amylase

20
Q

What is the method of action for alpha-amylase?

A

cleaves ALPHA-glycosidic bonds randomly in the middle of molecules

21
Q

What are the two most important activated sugars?

A

UDP-glucose and UDP-glucoronic acid

22
Q

What is the name of the enzyme that catalyzes the conversion of glucose-1-phosphate and UTP into UDP-glucose?

A

UDP glucose pyrophosphorylase

23
Q

What is the function of glycosyltransferases?

A

catalyze the the addition of an activated suger molecule to an existing branch polymer

24
Q

How does glycogen synthase function?

A

glycogen synthase catalyzes the addition of Glucose (from UDP-glucose) onto an existing glycogen molecule

25
Are glycosyltransferases limited to humans?
no. there are bacterial and fungal glycosyltransferases.
26
What is amylose?
A polymer of alpha 1,4-glucose
27
What is the function of SGLT?
activate transport of glucose and galactose into the intestinal epithelial cells
28
What is the function of GLUT2?
to release glucose from intestinal epithelial cells into the blood stream
29
How does fructose enter intestinal epithelial cells?
by facilitated diffusion using GLUT5
30
What is the function of GLUT1 and GLUT3?
basal glucose and galactose uptake by all cell types
31
Where is GLUT4 expressed?
muscle and adipose tissue
32
What can GLUT4 be induced by?
insulin
33
What is hexokinase inhibited by?
glucose 6-phosphate
34
What is the function of galactokinase?
phosphorylation of the C1 of galactose
35
Does glucose 6-phosphate inhibited the action of glucokinase?
no
36
Where is alpha-amylase located?
salivary and pancreatic secretions
37
What are the main breakdown products of alpha-amylase?
maltose and maltotriose
38
What is the function of galactokinase?
Phosphorylates the C1 of galactose prevents galactose from leaving the cell
39
What is a large difference between hexokinase and glucokinase regarding their role in sugar metabolism?
glucokinase is not inhibited by its end product. hexokinase is.