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DDS > powders and granules > Flashcards

powders and granules Flashcards

1
Q

can be taken orally

A

for internal use

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2
Q

solid powders can be applied to compromised areas of the body

A

for external use

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3
Q

powders are more stable than are liquid dosage forms c

A

composition

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4
Q

pass through a no. 8

A

very coarse (no.8)

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5
Q

pass through no. 20

A

coarse no. 20

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6
Q

pass through no. 40

A

moderately course no. 40

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7
Q

pass through no. 60

A

fine no. 60

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8
Q

pass through no. 80

A

very fine no. 80

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9
Q

typically fall within the range of 4 to 12 sieve size

A

granules

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10
Q

particles are passed by mechanical shaking

A

sieving

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11
Q

use of a calibrated grid background

A

microscopy

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12
Q
  • measuring the terminal settling velocity of particles
  • may be calculated from stake’s law
A

sedimentation rate

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13
Q

determined by the reduction in light reaching the sensor

A

light scattering

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14
Q

blending small amounts of powder

A

spatulation

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14
Q

used in small-scale preparation of ointments and suspensions

A

levigation

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15
Q

two or more powdered substances are to be combined to form a uniform mixture

A

blending powders

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15
Q
  • particle size of a solid substance to a finer state
  • increase in the specific surface area
A

comminution of drugs

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16
Q

grinding a drug in a mortar

A

trituration

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16
Q

pulsed laser is fired through an aerosolized particle spray

A

laser holography

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17
Q

passing them through sifters

A

sifting

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18
Q

small amount of a potent substance is to be mixed

A

geometric dilution

18
Q

mixing powder in a rotating chamber

A

tumbling

19
Q

some powders may become sticky or pasty or may liquefy when mixed together

A

eutetics

20
Q

Dispense the ingredients in tight containers and incorporate a desiccant packet or capsule when necessary.

A

Hygroscopic and Deliquescent Powders

21
Q
  • Should have a uniform, small particle size that will not irritate the skin when applied.
A

Topical Powders

22
Q

topical powders are consist of?

A

base or vehicle (cornstarch or talc)
adherent (magnesium stearate, calcium stearate, or zinc stearate)
active ingredient, along with an aromatic material.

23
Q

intended to be applied in a body cavity

A

Insufflated Powders

24
Q

Some medicated powders are administered by inhalation with the aid of dry powder inhalers (DPIs),

A

Aerosol Powders

25
Q

device used to administer an inhalation powder

A

DPI

26
Q

used with a device that aerosolizes and delivers an accurately metered amount.

A

inhalation powder

27
Q

which the patient takes by mixing with water or another beverages before swallowing;

A

acids and laxatives

28
Q

dissolved in warm water by the patient for vaginal use;

A

douche powders

29
Q

After a powder has been properly blended (using the geometric dilution method for potent substances), it may be divided into
individual dosing units based on the amount to be taken or used at a single time.

A

Divided Powders

29
Q

medicated powders for external application to the skin

A

anti-infectives or antifungals

29
Q

containing B-complex vitamins and other nutritional supplements.

A

brewer’s yeast powder

30
Q

weigh each portion of the powder individually. This

A

For potent drugs

31
Q
A
32
Q

block and divide method

A

for non-potent drugs

33
Q

a thin, semi-opaque paper with limited moisture resistance

A

vegetable parchment

33
Q

Powders containing neither volatile components nor ingredients adversely affected by air or moisture

A

simple bond paper

34
Q

a glazed, transparent paper, also with limited
moisture resistance

A

glassine

35
Q

a transparent waterproof paper

A

waxed paper

36
Q
  • a dosage form composed of dry aggregates of powder particles
  • are frequently compacted into tablets or filled into capsules
A

granules

37
Q

granules is Derived from Latin word: which means little grain

A

“Granulum”

38
Q

granules size

A

Usually pass in the 4 to 12 mesh size range

39
Q

particles are placed in a conical piece of equipment

A

Fluid Bed Processing

39
Q

Moisten the powder or powder mixture

A

Wet Method

40
Q

preparation of granules:

A

wet and dry method

41
Q

passed through a roller compactor and then through the granulating machine.

A

Dry Method

42
Q

“roll press”, processes a fine powder into dense sheets .

A

Roll compactor

DDS (9 decks)

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