powders and granules Flashcards
can be taken orally
for internal use
solid powders can be applied to compromised areas of the body
for external use
powders are more stable than are liquid dosage forms c
composition
pass through a no. 8
very coarse (no.8)
pass through no. 20
coarse no. 20
pass through no. 40
moderately course no. 40
pass through no. 60
fine no. 60
pass through no. 80
very fine no. 80
typically fall within the range of 4 to 12 sieve size
granules
particles are passed by mechanical shaking
sieving
use of a calibrated grid background
microscopy
- measuring the terminal settling velocity of particles
- may be calculated from stake’s law
sedimentation rate
determined by the reduction in light reaching the sensor
light scattering
blending small amounts of powder
spatulation
used in small-scale preparation of ointments and suspensions
levigation
two or more powdered substances are to be combined to form a uniform mixture
blending powders
- particle size of a solid substance to a finer state
- increase in the specific surface area
comminution of drugs
grinding a drug in a mortar
trituration
pulsed laser is fired through an aerosolized particle spray
laser holography
passing them through sifters
sifting