dosage form design Flashcards
is formulated invariably using drug and excipient(s) in appropriate proportions
Dosage form
rarely administered solely as pure substance but almost always given in the form of dosage form.
Active Pharmaceutical Ingredient (API)
combined to fabricate a final medicinal product of a desired dosage form
pharmaceutical product formulation
Develop and examine initial formulations of the product:
desired features
clinical effectiveness
formulation that best meets the goals for the product
Master Formula
Examines how the physical and chemical properties of a drug, the dosage form, and the route of administration influence the drug’s bioavailability and therapeutic effect.
biopharmaceutics
Studies the movement of drugs through the body, described by the processes of Absorption, Distribution, Metabolism, and Excretion (ADME).
pharmacokinetics
what is LADMER
liberation
absorption
distribution
metabolism
excretion
response
drug release from its formulation
liberation
biochemical drug modification
metabolism
movement of a drug from its size of administration
absorption
process of a drug traveling into different organs and tissues
distribution
desirable and undesirable
response
removal of the drug from the body
excretion
Refers to the proportion of a drug or other substance that enters the bloodstream and able to have an active effect in the body
bioavailability