Post Translation Modification Flashcards
1
Q
Protein disulphide isomerise
A
Correct cysteine residues in the correct confirmation from disulphide bonds
2
Q
chaperones
A
Fix misfolding
Retain unfolded state
3
Q
Post translational modification of collagen
A
Cleavage of signal sequence peptide
Hydroxylation of proline and lysine
N linked oligosaccharides
Galactose
Golgi
O linked glycosylation
Removalnof N and C terminals (tropocollagen)
4
Q
Ehlers danlos syndrome
A
Mutation in collagen V Lysyl hydroxylase deficiency Wekeaken conmective tissue Stretched skin Joint hypermobility
