Population genetics (notes) 4b Flashcards

1
Q

Population

A

Interbreeding groups of individuals that belong to the same species and live within a restricted geographical area

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2
Q

Population genetics

A

Concequences of mendelian genetics in a population- a shift from indiidual to population

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3
Q

The frequency of an—— in a population is often—– as the ration in a single cross

A
  • an allele
  • not the same
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4
Q

Darwin’s four conditions for evolution by natural selection (4)

*If these conditions are met, we will see change in allele frequencies and evolution

A
  1. Individuals within a species vary
  2. Some variation is passed to offsprings (Heritable)
  3. More offspring are produced than can survive and or/reproduce
  4. Survivial and reproduction is not random but related to phenotypic variation (gives certain individuals advantage
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5
Q

If darwin’s four conditions are met:

A

we will see changes in allele frequencies and evolution

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6
Q

Evolution by natural selection will not occur if (3)

A
  • there is no variation in species
  • the variation is not inheritable
  • Variation is heritable but has no fitness consequence
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7
Q

If there are no gene flow or variation being introduced into a population, and no variation being selected for we will….

A

not see any change in genetic variation

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8
Q

What is our null hypothesis for evolution?

A

There will be no change in allele frequencies over time

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9
Q

A population to be in abscence of evolution (no change in allele frequencies) has to have these conditions (5):

A
  1. A single locus with 2 alleles that does not change between generation (ie: no mutations/we do not introduce any new alleles)
  2. No gene flow
  3. Population is infinite
  4. Natural selection does not affect the alleles considered individuals have same fitness
  5. Random mating
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10
Q

Gene flow types (2)

A

Immigration+migration

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11
Q

Why population has to be very big?

A

This eliminates the effect of random processes that could change allele frequencies (ie: volcanic erupted)

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12
Q

genetic drift (2)
+ why its required for HWE

A

Allele frequencies can change by chance alone given the number of matings that can occur when you have a low number of individuals compared to a large number of individuals

the drifting of the frequency of an allele relative to that of the other alleles in a population over time as a result of a chance or random event

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13
Q

Random mating

A

regardless of phenotype at the locus of interest, all diploid individuals have the same fitness

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14
Q

elaborate what “natural selection does not affect the alleles considered” mean in HWE (3)

do not say there is no fitness consequence u dumbass

A

Probability of surviving to breed is the same
mating and fertilizing ability is the same

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15
Q

Hardy weinberg equlibrium equations

A

P+q=1

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16
Q

Probability of two independent events occuring together is the —- of their individual probabilities

A

product

17
Q

Frequencies of the three genotypes formula:

A
  1. AA-p^2
  2. Aa-2pq
  3. aa-q^2
18
Q

Because the gametes are haploid and mix randomly, if there is no selection at the genotype level:

A

all gametes goes back into gene pool

19
Q

under hardy weinberg the caculated genotype frequency with p^2+2pq+q^2 will always

A

be the same

20
Q

How do you tell if this population is in HWE?

A
  1. Calculate allele frequency
  2. Calculate expected genotype frequency
  3. Calculate the expected numbers under HWE using the expected genotype frequency and total population number
  4. Chi-sqaure test with given actual amount
21
Q

In general in a sample of n individuals the frequency of an allele is

A

The number of occurences of the allele divided by twice the number