Pneumocystis Flashcards

1
Q

Identify the characteristics of Pneumocystis that most resemble a protozoan.

A
  • Cyst and trophozoite stage- Protozoa?

- Does not grow on artificial media in the laboratory = protozoa?

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2
Q

Identify the characteristics of Pneumocystis that most resemble a fungus.

A

DNA sequence

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3
Q

Is pneumocystis jiroveci (formerly P. carinii) fungus or protozoa?

A

Fungus

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4
Q

What is the treatment for Pneumocystis infections?

A

Antibacterial agents (SXT- Trimethoprim-sulfamethoxazole), not antifungal or antiparasitic agents.

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5
Q

Which stain is more beneficial for recognizing cyst?

A

GMS is more beneficial and Giemsa, kinyoun or gram stains are also used but more difficult to recognize

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6
Q

Which stain is more beneficial for recognizing Trophozoites?

A

Giemsa stain

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7
Q

Describe the appearance of Pneumocystis trophozoites on giemsa stain

A

Pale blue cytoplasm with small mass of reddish nuclear chromatin

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8
Q

Describe the appearance of Pneumocystis cysts on GMS and Giemsa, kinyoun or gram stain.

A
  • May contain up to 8 intracystic bodies (clock face)
  • only cyst WALL stains Black with GMS - crinkled, raisin like, or punched out pingpong ball.
  • ONLY intracystic bodies of cysts stain with Giemsa, kinyoun, or gram stains
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9
Q

What is the best specimen to use for Pneumocystis jirvoeci identification?

A

usually from BAL specimen

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10
Q

Can Pneumocystis infection be found in healthy individuals?

A

YES (no symptoms)

- Antibodies usually acquired early in life

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11
Q

What is the significance of a diagnosis with Pneumocystis with undiagnosed AIDS patients?

A

Person who has Pneumocystis will be diagnosed with AIDS. Often first clue to new AIDS patients

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12
Q

Patients populations that are at increased risk for infection with Pneumocystis.

A
  • respiratory transmission

- healthy individuals

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13
Q

What is cause of Pneumocystis?

A
  • cause of pneumonia in immunosuppressed patients
    • AIDS/HIV & post transplant immunosuppression, leukemia patients on chemotherapy
    • Attaches/destroys alveoli
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