Plastic wound healing Flashcards
What are the stages of wound healing?
4 stages
- Haemostasis
- Inflammation
- Proliferation
- Remodelling
How long does epithelialisation take?
48hrs if 2 pieces of skin are cut and left to heal side by side
What happens during haemostasis?
Vasoconstriction
platelet aggregation
clotting cascade
fibrin deposition
What happens during days 1-4 of wound healing?
Inflammation stage
- chemotaxis attracts neutrophils on days 1 and 2
- macrophages arrive days 2-4
- epithelialisation begins
What happens over the first 3 weeks of wound healing?
Proliferation D4 - wk 3
- fibroblast proliferation
- ongoing angiogenesis
- ongoing epithelialisation
When does remodelling of a wound occur
from week 3 onwards
- collagen synthesis and breakdown occurs
- there is scar contraction
- after 60 days from wound injury the the scar will be at 80% of its pre-injury strength
What are the factors that affect wound healing?
There are local factors and general factors.
Local factors ; blood supply/ischaemia, infection, foreign body, haematoma, mechanical facets e.g. tension, previous radiation
General factors: smoking, chronic disease, steroid use, nutritional deficiencies, age, genetics
What is the difference between primary closure and secondary intention?
In primary closure the 2 edges are left together to heal as linear scar. In secondary intention the edges are not opposed together and the wound heals from the edges in by a combination of epithelialisation and contraction.
Which takes longer, healing by primary closure or secondary intention?
Secondary intention
What are the features of an ideal scar?
Flat
Thin
Colour match
Orientated along the relaxed skin tension lines
Types of abnormal scarring
Hypertrophic and keloid scars
What is the difference between a hypertrophic scar and a keloid scar?
Hypertrophic scars are elevated, red, enlarged scars that form within the borders of the original scar.
Keloid scars are elevated, raised, enlarged scars extending beyond the boundary of the original scar
What is the treatment of abnormal scars
pressure garments
silicone sheeting
steroid injections
re-excision
what skin type is more prone to keloid scar formation?
Darker skin groups
What is the primary goal of wound management?
To obtain a closed wound as quickly as possible to prevent infection and secondary deformity