Plasma Glucose: Fasting/Feeding Flashcards

1
Q

Abundance of Food causes what metabolic state?

A

Anabolic/Growth

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2
Q

Anabolic/Growth State relationship to plasma GH levels?

A

GH levels ↑

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3
Q

Scarcity of Food causes what metabolic state?

A

Catabolic/Glucose Sparing

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4
Q

Catabolic State relationship to plasma GH levels?

A

GH levels ↑

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5
Q

Fasting causes what 4 things to increase?

Increase of these things results in what?

A

glucagon
cortisol
epi
GH

liver glucose production

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6
Q

GH in fasting state causes what 2 things to decrease?

A

IGF (insulin growth factor)

insulin

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7
Q

High protein intake affect β cells how?

Can result in?

A

stimulates β cells -> ↑ insulin -> ↑ protein synth, ↑ glucose uptake by cells, ↓ glucose output by liver

Can result in hypoglycemia

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8
Q

High protein intake affects ⍺ cells how?

Can result in?

A

stimulates ⍺ cells -> ↑ glucagon -> ↑ glucose output by liver

Can results in hyperglycemia

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9
Q

Hypoglycemia prevented during high protein intake by what 2 things?

A

GH and glucagon

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10
Q

High protein intake results in increase of what?

↑GH results in?

A

↑insulin and ↑GH -> ↑IGF -> ↑protein synth, ↑lean body mass

↑GH -> ↑glucagon but ΦΔ in calorie storage

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11
Q

High carb intake results in?

A

↑ incretin -> ↑ insulin -> ↓ GH -> ↑ caloric storage

ΦΔ in IGF, protein synth, growth

Φ glucagon response cuz no AAs

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12
Q

Glucose infusion affects glucoregulatory hormone response to exercise how?

A

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13
Q

During the first few minutes of exercise, energy is pulled from?

A

glycogen and glucose (ATP then anaerobic)

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14
Q

During extended exercise, energy is pulled from?

A

FFA (aerobic oxidation)

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15
Q

IL-6 is?

Does what?

A

myokine

↑ glucose uptake/FA oxid in skeletal mm
↑ glucose production in liver/lipolysis in adipose

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16
Q

What happens to insulin during exercise?

A

↓ by catecholamines (SNS)

glucose infusion will NOT override

17
Q

Glucose uptake during exercise facilitated by?

A

contraction of skeletal mm

18
Q

What happens to glucose levels during intense acute exercise?

A

mm use stores glucose first then catecholamines stim large release of glu from liver (large ↑ in plasma glu level)

19
Q

Stim of insulin activation receptors causes what?

A

recruitment of GLUT4 transporters to surface of cells -> pull glucose into cell