Placebo effect Flashcards
Placebo which has inherent activity but not against the treated condition - may mimic the side effects of a drug which is being used in a clinical trial
Active placebo
Coined the term placebo
Beecher
Effect where placebo treatment results in negative effect
Nocebo effect
Decrease in placebo effect with repeated or chronic administration of placebo drugs
Placebo sag
Severity of illness where placebo effects are usually the strongest
Mild
Sum of an active drug’s pharmacological effect and its placebo effect
Net effect
Severity of pain where placebo effects are the strongest
Severe
Speed of placebo effect compared to pharmacological effects
Placebo effects occur faster
Placebo effect of capsules vs. pills
Capsules have a stronger placebo effect
Theory of placebo effect that states the disorders which placebo treatments work for are inherently episodic and would have improved with or without treatment
Natural remission theory
Theory of placebo effect that states that with each repeated measurement the mean of the sample will move from extreme values and become closer to the population mean
Regression to the mean
Effect of naloxone on placebo-induced analgesia
Partially reverses
Characteristics of placebo effect in depression
Starts abruptly
Occurs early in treatment
Less likely to persist
Effect of placebo effect when trials are blinded vs. unblinded
Larger for unblinded
Rate of placebo effect in studies over time
Increasing over time
