Pituitary Disorders Flashcards

1
Q

Hyperpituitarism Causes

A

Prolactin cell adenoma

GH cell adenoma

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2
Q

Hyperpituitarism Manifestation

A

Visual field abnormalities

Headach, N/V

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3
Q

Hyperprolactinemia

A

Most common hyper

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4
Q

Hyperprolactinemia Causes

A

Prolactinoma
Lack of dopamine inhibition (tumor, trauma)
Systemic disorder (renal, hypothyrodism)
Drug induced

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5
Q

Prolactinoma

A

Amenorrhea
Galactorrhea
Hypogonadism
Infertility (men and women)

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6
Q

Positive regulation of GH

A

GHRH

Ghrelin

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7
Q

Negative regulation of GH

A

Somatostatitn

IGF-1

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8
Q

Excess GH caused by

A
Pituitary Tumor (somatotroph adenoma - doesn't need GHRH reg just produces GH)
Hypothalamic tumor
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9
Q

Excess GH causes

A

Lean body mass
Diabetes
Polydispsia, glucosuria
Cardiac Hypertrophy

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10
Q

GH Deficiency Adults

A

Somatotrope damage

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11
Q

GH deficiency Children

A

GH Gene mutation
GHRH mutation
GH insensitiviy

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