Pharmacology of Adrenal Disorders Flashcards

1
Q

Glucocorticoid Replacement

A

Cortisol
Prednisone
Cortisone

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2
Q

Mineralcorticoid Replacement

A

Fludrocortisone

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3
Q

Glucocorticoid Replacement AE

A
Hyperglycemia
HPA suppression
Anti-inflammatory
Osteoporosis
Cushing's
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4
Q

Secondary insufficiency

A

Gluco not Mineral

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5
Q

Acute Adrenal Insufficiency

A

Endo Emergency

IV Cortisol

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6
Q

Cushing’s Treatment

A

Surgery
Radiotherapy
Steroidogenic

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7
Q

Steroidogenic Inhibitors MOA

A

Inhibit 11 beta hydroxylase

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8
Q

Steroidogenic Inhibitors drugs

A

Metyrapone (Metopirone)
Aminoglutethimide (Cytadren)
Ketoconazole (Nizoral)
Etomidate

My Armpits Kill E.coli

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9
Q

Adrenolytic Agents

A

Mitotane (Lysodren

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10
Q

GC Receptor Antagonists

A

Mifepristone (Mifeprex)

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11
Q

Conn’s Disease

A

Primary Hyperaldosteronism

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12
Q

Conn’s Treatment

A

MCR antagonists

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13
Q

MCR Antagonists

A

Spironolactone (aldactone)

Eplerenone (inspra)

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