Pituitary Flashcards
1
Q
What stimulates prolactin release?
A
TRH from the hypothalamus
2
Q
How does pituitary failure usually present?
A
Galactorrhoea
Amenorrhoea
Macroadenoma - bitemporal hemianopia
3
Q
Above what level of prolactin is a prolactinoma likely?
A
> 6000
4
Q
How is the pituitary gland tested?
A
Administering LHRH, TRH, and metabolic stress (hypoglycaemia)
5
Q
What will hypoglycaemia do to the pituitary?
A
Increase CRF and thus ACTH
Increases GHRH and thus GH
6
Q
Normal responses in a pituitary stress test
A
Cortisol > 550
GH > 10
7
Q
If ALL pituitary hormones are reduced, what do you need to do?
A
Urgently replace hydrocortisone
8
Q
What medication is used for a prolactinoma?
A
Dopamine agonist - bromocriptine or cabergoline