Enzymes and Cardiac Markers Flashcards

1
Q

In what order are intracellular enzymes released?

A

Cytosolic

Subcellular

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2
Q

Where is ALP found?

A

Liver
Bone
Intestines
Placenta

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3
Q

If GGT is raised as well as ALP, where is the ALP coming from?

A

Liver

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4
Q

What is the most widely used marker of muscle damage?

A
Creatine kinase
3 forms - dimers containing muscle and brain subunits
CK-MM = muscle
CK-MB = cardiac muscle
CK-BB = brain
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5
Q

Which cardiac drug can cause myopathy?

A

Statins

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6
Q

Which marker rises first in acute MI?

A

Myoglobin

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7
Q

Where is CK-MB found?

A

Mitochondria

Nucleus

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8
Q

Which biomarker can be used in cardiac failure?

A

BNP - ventricular function

Can be used to EXCLUDE

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