Pituitary

Question 1

what is released from the pituitary and what effect do they have

Answer 1

GHRH -> inc GH
TRH -> inc TSH, prolactin
Dopamine -> dec prolactin
LHRH/GnRH -> inc LH/FSH
CRH -> inc ACTH

Question 2

what is given at the start of pituitary function testing

Answer 2

give GnRH/LHRH, TRH and insulin

Question 3

what bloods are then taken in pituitary function testing

Answer 3

0, 30, 60mins - glucose, cortisol, GH, LH, FSH, TSH, T4, Prolactin
90 &120 mins - glucose, cortisol, GH

Question 4

what would be a normal result of pituitary function testing

Answer 4

cortisol inc by 550nM

GH inc by 10 IU/L

Question 5

if pituitary function testing showed decreased production of all hormones, what is suspected

Answer 5

prolactinoma

will also be very high prolactin

Question 6

how is a prolactinoma treated

Answer 6

urgent hydrocortisone

thyroxine, oestrogen, GH, DA ago (carbergoline/bromocriptine)

Question 7

how will a non functioning pituitary adenoma present

Answer 7

high prolacting (~2800) - but not as high as a prolactinoma