Physiology of Vision Flashcards

1
Q

What does the retina contain?

A

A sheet of light responsive photoreceptor cells

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2
Q

What does each cell of the retina have?

A

A distinct receptive field within the visual field

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3
Q

What does light coming from the receptive field generate?

A

An electrical response in photoreceptor cell = phototransduction

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4
Q

Where is the electrical response to light transmitted to?

A

Across the retina and visual structures terminating in the cortex

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5
Q

Where does perception of light occur?

A

The cortex

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6
Q

What is the direct pathway for signal transmission in the retina?

A

Photoreceptors - bipolar cells - ganglion cells

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7
Q

What are the lateral connections of the retina which influence signal processing?

A

Horizontal and amacrine cells

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8
Q

What is the role of horizontal cells?

A

Receive input from photoreceptors and project to other photoreceptors and bipolar cells

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9
Q

What is the role of amacrine cells?

A

Receive input from bipolar cells and project to ganglion cells, bipolar cells and other amacrine cells

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10
Q

What is the dark current the basis of?

A

Phototransduction

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11
Q

What happens with the dark current in the dark?

A

PNa = PK so Vm is therefore between ENa and EK

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12
Q

What happens with the dark current in the light?

A

PNa is reduced so Vm equals EK and hyperpolarises

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13
Q

What kind of change does the dark current cause?

A

Local and graded

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14
Q

What does light convert 11-cis-retinal to?

A

All-trans-retinal (activated form)

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15
Q

What effect does the greater convergence in the rod system have?

A

Increases sensitivity while decreasing acuity

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16
Q

What kind of light do rods see in?

A

Dim light

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17
Q

What kind of light do cones see in?

A

Normal daylight

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18
Q

What is centre surround organisation also known as?

A

Lateral inhibition

19
Q

What is the purpose of centre surround organisation?

A

Emphasises area of contrast = sharpens boundary between objects of different luminance

20
Q

How is light intensity detected in the visual system?

A

Detects local differences in light intensity, not the absolute amounts of light

21
Q

What type of gluR is involved in the on and off pathways?

A
On = inotropic gluR
Off = metabotropic gluR
22
Q

What effect does lateral inhibition have on ganglion cells?

A

Modifies the receptive fields of ganglion cells to have centre surround organisation

23
Q

What cells are primarily involved in centre surround organisation?

A

Horizontal and amacrine cells

24
Q

What does centre surround organisation help with?

A

Aids with localisation = exaggerates difference in stimulus intensity detected by adjacent neurons

25
Q

How do horizontal cells interact with groups of surround neurons?

A

Interconnect and sample the total amount of excitation in the surround and responds by releasing GABA

26
Q

What happens if there is low surround detected by horizontal cells?

A

Less GABA is released = response of centre on bipolar cell is thus higher

27
Q

How is retinal output processed?

A

Parallel processing = simultaneous input from two eyes, info compared in cortex

28
Q

Where does info about light and dark come from?

A

On centre and off centre ganglion cells

29
Q

What are the three different basic types of retinal ganglion cells?

A

M cells = movement
P cells = form and colour
Nonm-nonP cells = colour

30
Q

How is a binocular visual field created?

A

Each eye sees a part of the visual field (monocular visual field) but their visual fields overlap extensively

31
Q

Where do nerve fibres from the nasal half of each retina cross over?

A

The optic chiasm

32
Q

What do the two optic tracts allow?

A

Right and left visual fields to reach the left and right hemispheres separately

33
Q

What percentage of nerve fibres cross over?

A

60% cross over = nasal retina

40% don’t cross over = temporal retina

34
Q

Where is the entire visual field mapped?

A

Precisely mapped on to the primary visual cortex = has visuotopic organisation

35
Q

Is the scaling of the visual field on to the cortex constant?

A

No = about half of the cortex is dedicated to info from the relatively small fovea

36
Q

What does the visuotopic organisation of the primary visual cortex allow?

A

Mapping of lesions in the visual system

37
Q

Where do inputs to the striate cortex come from?

A

Magnocellular LGN neurons = layer IVCa
Parvocellular LGN neurons = layer IVCbeta
Konicellular LGN axons = bypass layer IV to synapse in layers II and III

38
Q

Where are binocular neurons found in the striate cortex?

A

Mostlyy layer IV

39
Q

What receptive fields are located in the striate cortex?

A

Cortical receptive fields

40
Q

How do the cortical receptive fields display orientation selectivity?

A

Respond to light/dark bars or edges only if in a particular orientation = peak frequency depends on angle

41
Q

Where are ocular dominance column located?

A

Present in VI

42
Q

Why is ocular dominance important?

A

Connections from the two eyes compete with each other

43
Q

Why are retinal synapses in the LGN unaffected by deprivation?

A

They are monocular

44
Q

What can monocular deprivation in the cortex during critical stages in development lead to?

A

Active afferents from one eye and lower activity from the other eye