Physiology: Female Sex Hormones: Dragatsis Flashcards
How many eggs does a woman usually have?
400,000
What is the process of ovulation steps?
Follicle Primordial follicle Corpus luteum Mature follicule (with ovum and antrium) Ovulation
Remaining: Corpus hemorrhagium (recently ovulated)
What does estrogen do? Stimulate growth and hormonal secretion of ovaries and follicals to stimulate the dominant follicle
f
What are the negative and positive feedbacks of estrogen on the hypothalamus and anterior pituitary/
Low: inhibit LH/FSH
Rising: sitim LH/FSH–>LH surge causes ovulation
high: Inhibitory!
Very low+ progesterone: inhibitory
What is used in birth control pills?
Very low E, and Progesterone
Estrogen does what to oviduct?
+: muscle, epithelium, motility, ciliary beating
Estrogen does what to uterus?
+ Myometrium growth and contractility
+ endometrium growth, spiral artery development
+blood supply
Estrogen does what to the cervix?
Production of thin, watery, clear mucus to allow sperm to get into uterus
What does estrogen do to uterine circulation?
Antivconstrictive dilatory
What is estrogen effect on the vagina?
+lubrication
+thickness of wall
+cornification
What does estrogen do to the mamary glands?
Branching of ducts
Fat deposition, connective tissue deposition
darkeing and growth of areola and nipples
TEST: What type of receptors does estrogen increase in the endometrium?
Progesterone receptors
Why is it important that estrogen increases progesterone receptors in the endometrium?
1; Alllows endometrium to increase nutrient secretion to fertilized egg (glycogen) before implantation, in response to increased progesterone in the luteal phase
2. allows implantation invasion
What do estrogen and testosterone do to bones?
Cause closure of epiphyseal plates at end of GH
How does estrogen effect cholesterol metabolism?
Good! High HDL and low LDL, anti-atherogenic