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Endocrine > Pathology: MEN and Pacreas Tumors > Flashcards

Pathology: MEN and Pacreas Tumors Flashcards

1
Q

Patient in coma, what to give them?

A

Glucose

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2
Q

What are the signs of hypoglycemia?

A

confusion, rapid heart beat, sweating, tremor, visual disturbance, confusion

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3
Q

MEN 1?

A

PPP

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4
Q

MEN 2a?

A

TPP

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5
Q

MEN2b?

A

TPMM

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6
Q

Patient comes in with abdominal pain, weight loss, jaundice. Complains of double vision and shakey hands. Then passes out. Ddx?

A

Insulinoma

  • Autonomic failure
  • EtOH
  • Insulin therapy
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7
Q

Most common metastasis of pancreas cancer?

A

Liver>Retroperitoneal lymph node>Bone

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8
Q

What are thresholds for Insulin, glucagon/Epi/NE/cortisol, and hypoglycemic symptoms?

A

80,70, 50

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9
Q

What is seen in histology of insulinomas?

A

“salt and pepper” chromatin
Sheets and islands of oval cells
Amyloid deposition

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10
Q

What can you treat insulinomas with?

A

Octreotide, sunitinib (mtor inh)

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11
Q

What is another pancreatic cancer other than insulinoma?

A

Gastoma

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12
Q

Patient comes in with GI ulcer and diarrhea, hypoglycemic.

A

Gastrinoma

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13
Q

What syndrome does gastrinoma lead to?

A

Zollinger-Elliston: GI ulcers

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14
Q

Patient comes in with rash on butt cheecks, anemia, swollen tongue, and newly onset diabetes. Dx?

A

Glucagonoma: increase Gluc, decrease insulin

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15
Q

What can be given to recussitate comatose patients?

A

Glucagon and glucose

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16
Q

Patient comes in with huge gallstones, smelly greasy diarrhea, and new diabetes mellitus. Dx?

A

Somatostatinoma of delta cells

17
Q

Patient comes in with watery diarhea, hypoKALEMIA, achlorhydria, hypovolemia, acidosis. Dx?

18
Q

What are the modifiable risk factors for atherosclerosis?

A

SHODDY: smoking, HTN, Obesity, Diabetes, Dyslipidemia

19
Q

Stones, Moans, Groans, Bones

A

Hypercalcemia

20
Q

Polyuria, polydipsia, polyphagia, fatigue, weight loss

A

Hyperglycemia

21
Q

Fatigue, weakness, nausea, parathesia, confusion

A

Hyperkalemia

22
Q

Lethargy, confusion, irritability, seizures, coma

A

Hypernatremia and HYPOnatremia

23
Q

Parathesias, muscle cramps, irritability, depression

A

Hypocalcemia

24
Q

Shakiness, sweatiness, nervousness, hunger, weakness

A

Hypoglycemia

25
Q

Fatigue, weakness, constipation, irritability, myalgia

A

Hypokalemia

26
Q

Monotonous round to oval cells with stippled chromatin pattern, minimal mitoses, arranged in nests, cords, strands, glands, sheets

A

Neuroendocrine tumors

27
Q

What is characteristic of PT adenoma?

A

Low fat content

28
Q

Primum non nocere

A

First, do no harm

Endocrine (15 decks)

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