Physiology Flashcards

1
Q

Endocrine glands will usually contain ducts. True/false?

A

False - ductless glands

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2
Q

What are the major endocrine organs?

A
Pituitary
Thyroid
Parathyroid
Adrenal
Pancreas
Ovaries
Testes
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3
Q

What are the hormone classifications?

A

Amines
Steroids
Peptides
Proteins

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4
Q

Describe autocrine signalling

A

The cell is both the signalling and target cell

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5
Q

Describe paracrine signalling

A

Signalling cell releases its signalling molecules which diffuse and meet target cells

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6
Q

Describe endocrine signalling

A

Signalling cell releases its molecules into the blood

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7
Q

Give an example of a complementary hormone action

A

Adrenaline, cortisol and glucagon all contribute to short term-exercise

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8
Q

Give an example of an antagonistic hormone action

A

Insulin works to lower blood sugar while glucagon works to increase it

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9
Q

Only steroid hormone not bound to protein is active. True/false?

A

True

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10
Q

Give some examples of carrier proteins

A

Cortisol-binding globulin
Thyroxine-binding globulin
Albumin

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11
Q

How do carrier proteins help to act as a hormone buffer?

A

Only free hormones can activate receptors meaning excess hormone is bound to by carrier protein

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12
Q

How does cortisol regulate its own secretion?

A

As it is carried back to the anterior pituitary and hypothalamus and suppresses release of the hormones involved in its secretion

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13
Q

The half-life of amines is seconds/minutes/hours?

A

Seconds

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14
Q

The half-life of steroids is seconds/minutes/hours?

A

Hours

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15
Q

The half-life of peptides is seconds/minutes/hours?

A

Minutes

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16
Q

What are the cell surface hormone receptors?

A

G-protein coupled receptors (GPCR)

Receptor kinases

17
Q

What are the intracellular receptors?

A

Nuclear receptors

18
Q

Class I nuclear receptor is activated by lipids/steroids and is found in the nucleus/cytoplasm?

A

Steroids

Cytoplasm

19
Q

Class II nuclear receptor is activated by lipids/steroids and is found in the nucleus/cytoplasm?

A

Lipids

Nucleus

20
Q

What activates hybrid class nuclear receptors?

A

Thyroid hormone (T3)

21
Q

Insulin binds via what type of receptor?

A

Receptor kinases