Physiology 5 Flashcards
Name the three ways in which carbon dioxide is transported in the blood.
- In solution
- As bicarbonate
- As carbamino compounds
What is the primary means by which carbon dioxide is transported in the blood?
As bicarbonate
Carbon dioxide is around __ times soluble than oxygen.
20
Which law influences how carbon dioxide dissolves in the blood?
Henry’s Law
Which enzyme catalyses the reaction of carbon dioxide and water to form hydrogen carbonate?
Carbonic anhydrase
Where is carbonic anhydrase found?
Red blood cells
Write a word equation for the conversion of water and carbon dioxide into hydrogen ions and bicarbonate ions.
CO2 + H20 H2CO3 H+ + HCO3-
Carbon dioxide diffuses from the tissues into red blood cells down a ___ ___ gradient.
partial pressure
What is a chloride shift?
The transfer of bicarbonate and chloride ions out of / into a red blood cell respectively
Hydrogen ions act as a ___ in red blood cells.
buffer
Name a terminal amine group which carbon dioxide binds with to form a carbamino compound.
Globin (to form carbamino-haemoglobin)
Formation of carbamino-haemoglobin (depends / does not depend) on enzyme activity.
does not depend
What type of Hb can bind increased amounts of carbon dioxide?
Reduced Hb
Hb / HbO2 can bind more carbon dioxide.
Hb
What is the Haldane Effect?
Removing oxygen from Hb increases the ability of Hb to bind carbon dioxide and CO2-generated H+ ions