Physiology Flashcards
What is the relative viscosity of blood?
3x
What is the relative viscosity of plasma ?
1.5x
Give an example of a hematopoietic growth inducer?
IL-3
Where is erythropoietin produced?
90% kidney (10% liver)
What hormone increases EPO production?
Epinephrine (& norepinephrine)
When is maximum epo production reached after stimulation ?
1-5 days
Where is B12 absorbed ?
In the ileum
How does pernicious anemia differ from megaloblastic anemia?
Pernicious is deficiency in intrinsic factor not the vitamin itself
What is the volume of RBCs?
90 um^3
Percentage of iron used in hemoglobin?
64%
Percentage of iron used in myoglobin?
4%
Percentage of iron stored as ferritin?
15-30%
Name of macrophages in skin?
Langerhans
Name of macrophages in placenta?
Hofbauer
Name of macrophages in bones?
Osteoclasts
Name of macrophages in lymphoid organs?
Dendritic cells
Name of macrophages in intestines?
M cells
Name of macrophages in brain?
Microglia
Name of macrophages in alveoli?
Dust cells
What do macrophages produce to stimulate inflammation?
TNF & IL-1
What is normal bleeding time?
1-6 minutes
What is normal clotting time?
6-10 minutes
Most common blood type?
O
Least common blood type?
AB
Percentage of Rh+ factor in all population and black population?
85% and 100%
