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HLS > Anemia > Flashcards

Anemia Flashcards

1
Q

How is MCV calculated?

A

Hematocrit / RBC count

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2
Q

What is the unit of MCV

A

FL

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3
Q

Unit of measuring hemoglobin level?

A

g/dl

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4
Q

Unit of measuring RBC count?

A

Millions/mm^3

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5
Q

How is MCH measured?

A

Hemoglobin level / RBC count

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6
Q

How is MCHC measured?

A

Hemoglobin level / Hematocrit

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7
Q

Normal value of RDW?

A

<15%

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8
Q

What is anisocytosis ?

A

RDW >15% (RBCs of different sizes)

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9
Q

What stain do we use for a peripheral blood smear?

A

Giemsa

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10
Q

Normal range for reticulocytes?

A

0.5~1.5%

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11
Q

Normal range for corrected reticulocytes ?

A

2-3

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12
Q

Where is iron absorbed ?

A

Duodenum

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13
Q

What is poikilocytosis?

A

RBCs having different shapes

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14
Q

Signs of anemia (not symptoms)

A

Koilonychia
Pica
Tachycardia

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15
Q

What viruses target erythropoietic stem cells?

A

HIV,HBV,EBV,CMV,B19

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16
Q

Inheritance pattern of fanconi anemia?

A

Autosomal recessive

17
Q

How to treat aplastic anemia?

A

Bone marrow transplant

18
Q

Causes of pancytopenia?

A

Aplastic anemia and megaloblastic anemia

19
Q

What PNH stand for?

A

Paroxysmal nocturnal hemoglobinuria

20
Q

Which is more common; intravascular or extravascular hemolytic anemia?

A

Extravascular

21
Q

Inheritance pattern of hereditary spherocytosis?

A

Autosoma ; 75% dominant
25% recessive > worse

22
Q

Inheritance pattern of HbS and HbC diseases

A

Autosomal recessive

23
Q

What is most common familial hemolytic anemia in the world?

A

Sickle cell

24
Q

Describe the mutation leading to sickle cell disease?

A

Point mutation causing glutamate to be replaced for valine

25
Q

Describe the mutation leading to HbC?

A

Point mutation causing glutamate to be replaced for lysine

26
Q

Signs of extra-medullary hematopoiesis

A

Hepatospleenomegaly

27
Q

How to identify thalassemia on a blood smear?

A

Target cell + Basophilic stippling

28
Q

Inheritance pattern of thalassemia?

A

Autosomal recessive

29
Q

Hemoglobin level of major thalassemia ?

A

3-6 g/dl

30
Q

Hemoglobin level of minor thalassemia ?

A

9-11 g/dl

31
Q

What is favism?

A

The reaction of G6PD deficiency patients when eating fava beans

32
Q

Inheritance pattern of G6PD?

A

X linked

33
Q

Features of G6PD blood smear?

A

Heinz bodies > Bite cells

34
Q

What does MAHA look like on a blood smear?

A

Schistocytes

35
Q

How many people suffer from G6PD?

A

200 million

HLS (13 decks)

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