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HLS > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Route of administration of UFH prophylaxis?

A

Subcutaneous

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2
Q

Route of administration of UFH?

A

IV

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3
Q

Route of administration of LMW Heparin?

A

Subcutaneous

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4
Q

What could happen if heparin is given IM?

A

Hematoma

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5
Q

When is LMWH monitored?

A

Obesity
Pregnancy
Renal insufficiency

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6
Q

How is LMWH monitored ?

A

Anti Xa

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7
Q

What allergies should be checked before giving heparin?

A

Cow & pigs

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8
Q

Which surgery is heparin contraindicated in ?

A

Lumber puncture

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9
Q

What is the half life of fondaparinux ?

A

15 hours

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10
Q

How often should fondaparinux taken?

A

Once daily

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11
Q

What is fondaparinux indicated for ?

A

Venous thromboembolism

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12
Q

Univalent vs Bivalent direct thrombin inhibitors

A

Univalent: reversible & 1 site
Bivalent: irreversible & 2 sites

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13
Q

What do we give a patient with a history of HIT?

A

Argatroban

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14
Q

Route of administration of argatroban?

A

IV

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15
Q

Route of administration of dibagtron?

A

Oral

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16
Q

What is bivalirudin indicated for ?

A

Percutaneous coronary angioplasty

17
Q

What is dibagatron indicated for?

A

Prophylaxis from venous thromboembolism in patients who underwent hip / knee replacement

18
Q

What is heparin’s antidote?

A

Protamine

19
Q

What is dibagatron antidote?

A

Idarucizumab

20
Q

Route of administration of rivaroxiban?

A

Oral

21
Q

What anticoagulant do we give patients with nonvalvular atrial fibrillation to prevent stroke?

A

Rivaroxaban / Apixaban

22
Q

What anticoagulant do we give patients after knee/hip replacement to prevent venous thromboembolism?

A

Dibagatron / Rivaroxaban

23
Q

What is the antidote for rivaroxaban?

A

andexanet alpha

24
Q

What is the half life of warfarin?

A

36 hours

25
Q

Why is warfarin contraindicated in hypothyroidism?

A

Slower turnover rate of clotting factors

26
Q

What is cangrelor indicated for?

A

Coronary interventions

27
Q

What is the administration route of cangrelor?

A

IV

28
Q

What do we use for prophylaxis from thromboemboli for patients with prosthetic heart valves?

A

Warfarin + dipyridamol

29
Q

What can be used for percutaneous coronary intervention?

A

Bivalirudin or Abciximab

30
Q

What is the route of administration of GPIIb/IIIa inhibitors?

A

Parenteral

31
Q

What can we use to prevent cerebrovascular ischemia ?

A

Aspirin + dipyridamol

32
Q

What can we use for peripheral arterial disease?

A

Cilostazol / Vorapaxor

33
Q

What is the antidote for fibrinolytic drugs?

A

Aminocaproic acid

34
Q

What species is mycophenolate isolated from?

A

Penicillium glaucus

35
Q

Anticoagulant with longest half life?

A

Vorapaxor

36
Q

What anticoagulant do we use for acute cornoary syndrome

A

Ticagrelor + Aspirin
Or GP IIb/IIIa inhibitors

HLS (13 decks)

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