Physiology Flashcards
Severe vomitting causes:
Metabolic alkalosis (Vomitting = Loss of HCL)
Which hormone increases during the first trimester of pregnancy?
HCG
Which law keeps the lungs from overinflating?
Hering Breuer
Inspiration leads to a ________ in alveolar pressure
Decrease
The epididymus is located _____ the testes and is where the ______ is stored
Above; Sperm
Aerobic glycolysis _______ skeletal muscle blood flow
Increases
Interleukin I is responsible for _______ ; Interleukin II is responsible for ______
Macrophages/monocytes; Lymphocytes
What is the function of gap junctions?
Direct diffusion of ions and small molecules to maintain heart rhythm
A decrease in blood protein leads to _______ and a _______ of oncotic pressure
Edema; decrease
What happens during rigor mortis, in terms of ATP production?
ATP decreases in skeletal muscle
The sarcoplasmic reticulum is important for:
Muscle contraction
Ketosis triggers: Metabolic _______ and Respiratory ________
Acidosis; Alkalosis
Large vessel that has valves
Vein
ADH has it’s greatest effect on the ______________
Collecting duct
Which of the following is produced in the zona glomeulosa of the adrenal cortex?
A. Aldosterone
B. Epinephrine
C. Cortisol
D. Serotonin
A. Aldosterone (Absorbs Sodium/excretes potassium)
Damage to the liver can lead to:
A. Decreased lipid and protein metabolism
B. Decreased lipid digestion
B. Decreased lipid metabolism
D. Decreased lipid digestion and synthesis, and impaired blood sugar regulatoin
D. Decreased lipid digestion and synthesis, and impaired blood sugar regulatoin
Which of the following are the quickest adaptors
A. Pacinian corpuscles
B. Meissner’s corpuscles
C. Merkel’s Corpuscles
D. Hair Follicles
A. Pacinian corpuscles
Which of the following is inhibitory?
A. Norepinephrine
B. Glutamate
C. Nitric Oxide
D. Dopamine
D. Dopamine
Decreased interpleural pressure causes;
A. Expiration
B. Inspiration
C. Hypoventilation
D. Hyperventilation
B. Inspiration
What controls the pace of the heart?
A. Atrioventricular node
B. Sinoatrial node
C. Pukinje Fibers
D. Myocardium
B. Sinoatrial node
What produces the first beat of the heart?
A. Semilunar valve closing
B. Atrioventricular valves opening
C. Atrioventricular valves closing
D. Semilunar valve opening
C. Atrioventricular valves closing
What is the function of surfactant?
A. Increase surface tension
B. Decrease surface tension
C. Reduce intradural pressure
D. Increase tidal volume
B. Decrease surface tension
Oxytocin stimulates:
A. Milk let down and growth of the corpus luteum
B. Milk let down and breast development in pregnancy
C. Milk let down and secondary sexual characteristic development
D. Milk let down and uterine contraction
D. Milk let down and uterine contraction
According to the Frank-Starling law, the critical factor controlling stroke volume is:
A. Degree of stretch the cardiac muscle cells just before they contract
B. Heart rate
C. Stroke volume amplitude
D. Autonomic nervous system regulation
A. Degree of stretch the cardiac muscle cells just before they contract
What point of the myosin protein does ATPase attach?
A. Tail
B. Head
C. Body
D. Hillock
B. Head
Vital Capacity includes
A. Functional Respiratory Capacity + Tidal Volume
B. Respiratory Capacity + Residual Volume
C. Inspiratory Reserve + Residual Volume
D. Inspiratory Reserve + Tidal Volume + Expiratory Reserve
D. Inspiratory Reserve + Tidal Volume + Expiratory Reserve
Which of the following characteristics are similar for smooth muscle and skeletal muscle?
A. Length of actin filaments
B. Contracts in response to action potentials, which begin following the stimulation by motor neurons
C. Calcium ions are crucial to contraction
D. Strength of contraction per cross sectional area of muscle
C. Calcium ions are crucial to contraction
The myocardium plateau is due mainly to the:
A. Delayed influx of calcium
B. Calmodulin present in myocardium
C. Sodium-calcium exchange channels
D. Summation of repetitive action potentials from the Sinoatrial node
C. Sodium-calcium exchange channels
In which portion of the renal tubules does the majority of absorption take place?
A. Collecting duct
B. Loop of Henle
C. Proximal Convoluted Tubule
D. Distal Convoluted Tubule
C. Proximal Convoluted Tubule
An influx of sodium causes:
A. Repolarization
B. Hyperpolarization
C. Depolarization
D. No polarization
C. Depolarization
What blood test finding best describes respiratory acidosis?
A. Increased pH
B. No change in pH
C. Decreased pH
D. Very little change in the pH
C. Decreased pH
Post synaptic contraction of skeletal muscle is due to:
A. Release of Ca2+ from sarcoplasmic reticulum
B. Ca2+ influx into the cell at the myo-synaptic junction
C. Influx of Sodium
D. Efflux of Potassium
A. Release of Ca2+ from sarcoplasmic reticulum
The juxtaglomerular apparatus releases renin in response to:
A. Decreased pressure in the afferent arteriole
B. Constriction of efferent arteriole
C. Decreased sodium in the proximal convoluted tubules
D. Decreased potassium in the proximal convoluted tubules
A. Decreased pressure in the afferent arteriole
Chromaffin cells are developed from ______; & are associated with the _____ part of the autonomic nervous system:
A. Neural crest; parasympathetic
B. Neural crest; sympathetic
C. Mesoderm; sympathetic
D. Mesoderm; parasympathetic
B. Neural crest; sympathetic
Hyperventilation will cause;
A. Respiratory alkalosis
B. Respiratory acidosis
C. Metabolic acidosis
D. Metabolic alkalosis
A. Respiratory alkalosis
The peptide believed to be an important CNS neurotransmitter in pain sensation pathways is:
A. Bradykinin
B. Enkephalin
C. Substance P
D. Dopamine
C. Substance P
Stenosis of the mitral valve can result in hypertrophy of the _____, due to increased mechanical resistance during contraction
A. Left atrium
B. Right atrium
C. Left ventricle
D. Right ventricle
A. Left atrium
All of the following are regulated by the parasympathetic nervous system EXCEPT:
A. Sudoriferous glands
B. Exocrine glands
C. Mucosal glands
D. Sublingual glands
A. Sudoriferous glands (sweat glands)
Depolarization is associated with the ________ phase:
Ascending
Repolarization is associated with the _______ phase:
Descending phase
In moving an action potential, Calcium releases ________
Neurotransmitter
The resting state of an action potential is said to be ______
Polarized
Which is the MC synapse point?
Axodendritic
An efflux of Potassium is associated with:
Repolarization
MS, Posterolateral sclerosis and ALS are _______ diseases
Demyelinating
Sclerosis means that _____ is gone & replaced by _____
Myelin; Scar tissue
Myelin is made of _____
Fat
Which vitamin is important for myelination
Vitamin B12
Pressure, encapsulated mechanoreceptor
End bulbs of Krause; Pacinian
Mechanoreceptor associated with temperature perception, pressure, encapsulated & multi branched, 2-5 degrees perception
Ruffini Corpuscles
Only Receptors that are not encapsulated
Merkel discs
Receptor associated with pressure, vibration, encapsulated
(“Phasic receptor”/“Quick Adaptor”)
Pacinian Corpuscles
Which ANS system is associated with CN III, VII, IX, X & Sacral plexus S2, S3, S4?
Parasympathetics
Sympathetics are associated with _______
Chain ganglion
-Sympathetics have a: _____ Pre/_____ Post
Short/Long
-Parasympathetics have a: ____ Pre/_____ Post
Long/Short
Sympathetics Post ggl release:
Epinephrine/Norepinephrine
Influx of Sodium
Depolarization
Efflux of Potassium
Repolarization
No A-P possible
Absolute refractory
A-P available with increase potential
Relative refractory
Many synapses in a single cell
Spatial summation
Rapid succession of A-P, few synapses
Temporal
________ Cells release glycine, prevent excessive muscular
Renshaw
Heschl’s gyrus is associated with which sensory area?
Auditory
Sensory area associated with “Receptive” portion of language
Wernicke’s
Motor area associated with “expressive” portion of language
Brocha’s
Coordination of muscle contractions
Cerebellum
Superior colliculi is responsible for:
Vision
Inferior colliculi is responsible for:
Auditory
The inferior colliculi originates from which CNs
III, IV
Area of the brain concerned with breathing
Pons
The pons is originates from which CNs
V, VI, VII, VIII
The medulla originates from which CNs
VIII, IX, X, XI, XII
Dark spots->Aging->Product oxidation
Lipofuscin
Sinus node “dies” and AV node takes over
Ectopic focus
Arteries have ____; Veins have _____
Muscles; Valves
The pulomnary vein has _____ blood
Oxygenated
The QRS complex leads to ventricular _________ and atrial _________
Contraction; relaxation
Na/K+ pump functions by:
Maintaining resting state of heart
Match these ECG components with their function: P wave , S-T interval, QRS complex , T wave
- Ventricular repolarization
- Ventricular depolarization & atrial repolarization
- 0.04 to 0.06s
- Atrial depolarization
- T wave
- QRS Complex
- S-T Interval
- P Wave
Depolarization is concerned with _____; Repolarization is concerned with ______
Work; Rest
Closing of mitral/tricuspid valve (A-V valves) creates:
S1 sound
Closing of aortic & pulmonic (semilunars) creates:
S2 sound
______ murmurs are the most clinically significant
Diastolic
Aortic Regurgitation = Mitral _______
ARMS
Stenosis
Pulmonic_________ = Tricuspid Stenosis
Regurgitation
PRTS
Force exerted by fluid against a wall
Hydrostatic Pressure
Created by plasma proteins unable to move through the capillary membrane
Osmotic pressure
Match these laws with their descriptions: Frank-Starling’s Law, Davis’ Law, Boyle’s Law
- Muscle will increase in size when used
- Stroke volume increases in response to volume of blood filling the heart
- Inversely proportional relationship between pressure & volume of a gas, if temp kept constant within a closed sys.
- Davis’ Law
- Frank-Starling
- Boyle’s
Proteins in blood
Albumin & globulin
Precursor platelets are ______
Megakaryocytes
Which WBC is in the highest quantity?
Neutrophils (60%)
“Never Let My Engine Blow, 60-30-8-3-0”
Neutrophils->Lymphocytes->Monocytes->Eosinophils->Basophils
Granulocytes
Basophils, Eosinophils, Neutrophils
“BEN; Uncle Ben’s Rice”
Agranulocytes
Lymphocytes, monocytes
Kupffer Cells are macrophages that are found in the:
Liver
Stores Ca++ to be released to skeletal muscle
Sarcoplasmic reticulum
Thick, H zone, Crosses bridges
Myosin
ATPase will attach to the myosin _____
Head
Thin, F-actin filament + tropomyosin + troponin
Actin
Covers F actin’s binding sites
Tropomyosin
“MOM”
Binds calcium and moves tropomyosin off binding sites
Troponin
“DAD”
Troponin is found in:
Skeletal & Cardiac muscle
Smooth muscle consists of:
Actin, myosin and sarcoplasmic reticulum
______ is needed for smooth muscle contraction
Calmodulin