Physio & Psychopharmacology Flashcards

1
Q

Build up of (…) in the cerebral (…) can cause (…).

A

cerebrospinal fluid, ventricles, hydrocephalus

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2
Q

The hypothalamus controls the (…) system and (…) glands, mediates basic (…), and regulates (…) expression. The (…) nucleus (SCN) regulates the circadian rhythms.

A

autonomic nervous system, endocrine, drives, emotional, suprachiasmatic

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3
Q

“I hear blue” and “smell someone yelling” are examples of (…), the rare condition of one sensory modality triggers a sensation in another.

A

synesthesia

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4
Q

Hypoglycemia involves low (…) and excessive (…) production by the (…). Symptoms include: dizziness, (…), blurred vision, anxiety, (…), and (…).

A

blood glucose, insulin, pancreas, headaches, depression, confusion

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5
Q

Three emotion areas of the brain are: (…), (…), and (…).

A

amygdala, hypothalamus, cerebral cortex

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6
Q

The (…) facilitates perception and expression of anger, (…), sadness, (…), and attaches these emotions to (…). It is in the (…) system.

A

amygdala, fear, happiness, memory, limbic

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7
Q

The (…) translates emotions into (…) response.

A

hypothalamus, physical

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8
Q

The (…) processes emotions hemispherically, with the (…) hemisphere processing (…) emotions and the (…) processing (…) emotions.

A

cerebral cortex, left, positive, right, negative

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9
Q

(…)-(…) Syndrome results from a lesion in the (…) and the following symptoms: altered (…) habits, (…), and reduced (…) and (…).

A

Kluver-Bucy Syndrome, amygdala, dietary, hypersexuality, fear and aggression

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10
Q

The (…) is involved in extrapyramidal control of motor activities. Damage can result in (…), characterized by (…) speech, severe (…), and a loss of balance.

A

cerebellum, ataxia, slurred, tremors

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11
Q

The (…) lobe houses the (…) cortex. Visual (…) is the inability to recognize familiar objects.

A

occipital, visual

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12
Q

The (…) is another limbic system structure involved in (…) and (…) memory, as well as the (…) of declarative memories.

A

Hippocampus, spatial and explicit, consolidation

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13
Q

MAOI stands for (…). It deactivates dopamine, (…), and serotonin. A (…) crisis is a side-effect can occur with foods with the amino acid (…). Symptoms include: stiff neck, rapid heart rate, (…), (…), (…), and sensitivity to light.

A

monoamine oxidase inhibitor, norepinephrine, hypertensive, tyramine; nausea, vomiting, sweating

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14
Q

Opioids or (…)-(…) have sedative and (…) properties. Used to treat (…) and as a (…) suppressant. Opiod peptides are also known as (…).

A

narcotic-analgesics, analgesic, diarrhea, cough, endorphines

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15
Q

Older adults often experience an (…) sleep phase, meaning they go to bed (…) and wake up (…).

A

advanced sleep phase (ASP), earlier, earlier

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16
Q

There are two basic types of seizures or epilepsies: (…) and (…). The later includes (…) type that does not involve LOC, while (…) type involves some alteration in consciousness.

A

general and partial, simple, complex

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17
Q

Generalized seizures are bilaterally (…) and do not have a (…) onset. They include (…) and (…) seizures. Grand mal include muscle contraction and rhythmic shaking, while petit mal are (…) with LOC but without (…) symptoms.

A

symmetrical, focal, tonic-clonic and absence, brief, motor

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18
Q

Type A personality and heart disease is most consistently linked to (…) and (…).

A

hostility and anger

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19
Q

Huntington’s Disease is an autosomal (…) disorder.

A

dominant

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20
Q

Tourette’s Disorder is associated with both (…) symptoms as well as (…) and (…).

A

ADHD, obsessions and compulsions

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21
Q

Sides effects of Benzo’s include: (…), memory loss, and (…) impairment.

A

confusion, psychomotor

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22
Q

Parkinson’s disease is characterized by (…), muscular rigidity, (…), akinesia, and speech difficulties. Symptoms temporarily relieved by (…), a (…) agonist. Caused by a degeneration in (…)-containing cells in the (…) nigra.

A

tremor, akathisia, L-dopa, dopamine, dopamine, substantia

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23
Q

akathisia is known as “cruel (…)”, akinesia is a reduction or absence of (…) movement

A

restlessness, spontaneous

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24
Q

Sleep EEG patterns include (…), beta, (…), delta, and REM. In stage (…), alpha are replaced by beta. Stage (…), (…) waves are interrupted by sleep (…) and (…)-complexes.

A

alpha, theta, one(1), two(2), theta, spindles, K-complexes

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25
Q

Newborns start with (…) sleep, that turns into (…) sleep. This reverses by (…) months. Adulthood sees the decline of total sleep time, stage (…) sleep, and (…).

A

REM, NREM, three, 4, REM

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26
Q

The (…) theory of color vision includes three primary colors: (…). The (…)-(…) theory postulates three bipolar receptors: (…). In the later, some cells are (…), while the other is (…).

A

trichromatic; red, blue, and green; opponent-process, red-green, yellow-blue, and white-black; excited, inhibited

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27
Q

The (…) (…) are subcoritcal structures involved in planning, (…), and coordinating (…) movements. Linked to Hungtington’s, (…) disease, (…) disorder, (…), and ADHD.

A

basal ganglia, organizing, voluntary, Parkinson’s, Tourette’s, OCD

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28
Q

The Basal Ganglia includes four structures: caudate nucleaus, (…), (…), and substantia nigra.

A

putamen, globus pallidus

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29
Q

Depth perception relies on (…) and (…) cues. Retinal (…) is a (…) cue, suggests the closer the object, the greater the (…) of the two images.

A

binocular, monocular, disparity, binocular, disparity

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30
Q

Huntington’s Disease involves (…), (…), and motor symptoms. (…) appear first. Early motor symptoms include (…), clumsiness, followed by “piano-playing” movements. Due to loss of (…)-secreting neurons and (…) excitotoxicity in the (…) (…).

A

emotional, cognitive, emo-cog, fidgeting, GABA, glutamate, basal ganglia

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31
Q

The (…) is a hindbrain structure regulating (…), heartbeat, and (…).

A

medulla, breathing, blood pressure

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32
Q

CT and MRI are (…) techniques, PET, SPECT, and fMRI are (…).

A

structural, functional

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33
Q

Postconcussional disorder requires a (…) trauma with LOC, (…) disturbance, and 3+ symptoms for at least (…) months (e.g. headache, irritability).

A

head, cognitive, three

34
Q

The (…) nervous system governs (…) activities. Information travels from (…) nerves to CNS and/or (…) nerves to (…) muscles through the CNS.

A

somatic, voluntary, sensory, motor, skeletal

35
Q

3 Theories of Emotion: 1) James-(…): emotions represent perceptions of (…) reactions to (…) stimuli; (…)-Bard: emo and body simultaneous resulting from (…) stimulation; (…): emo are universal, differ by how they are (…) or (…) - primary, secondary, and (…).

A

James-Lange, bodily, sensory, Cannon-Bard, thalamic, Lazarus, interpreted or appraised, re-appraisal

36
Q

3 Aphasias: Broca’s, Wernicke’s and (…). (…) aphasia is from damaged (…) (…). It does not affect (…), but does result in (…), paraphasia, and impaired repetition.

A

Conduction x 2, arcuate fasciculus, comprehension, anomia

37
Q

Apraxia, sensory neglect, and dominant hemisphere aphasia are stroke symptoms from a blocked (…) cerebral artery.

A

middle

38
Q

memory loss, unilateral cortical blindness, and visual agnosia are stroke symptoms from a blocked (…) cerebral artery.

A

posterior

39
Q

apathy, depression, confusion, bowel and bladder incontinence, mutism are stroke symptoms from a blocked (…) cerebral artery.

A

anterior

40
Q

Learning and memory: (…) lobes, (…), (…), prefrontal cortex, and (…).

A

temporal (encoding, storing, retrieval LTM), hippocampus (transferring STM to LTM), amygdala (learning about rewards and punishments), thalamus (transferring info to neocortex)

41
Q

MS involves the degeneration of (…). Initial symptoms include: optic neuritis, (…) impairments, (…) abnormalities, and fatigue. Later symptoms include (…), (…) problems, mood symptoms, and (…) impairment.

A

myelin, motor, sensory, tremors, speech, cognitive

42
Q

(…) Circuit mediates the experience and expression of (…). It includes the hippocampus, (…) bodies, thalamus, and (…) gyrus.

A

Papez’s, emotion, mammillary, cingulated

43
Q

The (…) lobe contains the primary auditory cortex.

A

temporal

44
Q

General Adaptation Syndrome: response to stress is mediated by the (…)-(…) secretions and 3 stages: alarm reaction, (…), and (…). Can cause death if prolonged.

A

adrenal-pituitary (cortisol), resistance, exhaustion.

45
Q

Long-term (…) (LTP) is a physiological process involving the modification of (…) synapses, at (…) receptors in the (…). Inhibiting (…) at the time of learning prevents LTP.

A

potentiation, nerve, glutamate, hippocampus, protein or RNA

46
Q

Naltrexone (e.g. (…)) is an (…) antagonist that blocks craving for (…). 4 Side effects include: (…) cramping, (…), (…), and (…).

A

Vivitrol, opioid, alcohol, abdominal, nausea, vomiting, insomnia

47
Q

Damage to the (…) lobe can cause apraxia, (…), and (…) syndrome, which involves (…) agnosia, (…), and (…).

A

parietal lobe, anosognosia, Gerstmann’s syndrome, finger, agraphia, and acalculia

48
Q

Anosognosia is the inability to recognize (…).

A

one’s own neurological symptoms or other disorder

49
Q

Wernicke-Korsakoff Syndrome begins with mental confusion, (…) movements, and (…); followed by Korsakoff’s symptoms.

A

abnormal eye, ataxia

50
Q

Beta-Blockers ((…)) diminish (…) excitatory response to the hormones (…) and (…). Used to treated heart conditions and anxiety. 4 sides effects include: (…), (…), (…), (…).

A

Propranolol, cardiovascular, epinephrine, norepinephrine, bradycardia, nausea, diarrhea, dizziness

51
Q

Primary hypertension accounts for (…)-(…)% of all cases of high blood pressure and is (…) due to a known physiological cause.

A

85-90%, NOT

52
Q

(…) (…) Syndrome is rare, but potential fatal side effect of antipsychotic drugs. It involves: (…), (…), (…), and altered consciousness. The drug must be stopped (…) to avoid death.

A

Neuroleptic Malignant, muscle rigidity, tachycardia, hyperthermia, as soon as symptoms develop

53
Q

There are 3 Psychophysical laws: (…), (…), and (…). (…)’s law states that the (…) (…) difference in stimulus intensity is a (…) (…) of the initial stimulus intensity.

A

Weber, Fechner, and Steven’s Power Law; Weber’s, just noticeable, constant proportion

54
Q

Fechner’s law states that physical stimulus changes are (…) related to their (…) sensations.

A

logarithmically, subjective

55
Q

Steven’s Power Law proposes that the (…) of the sensation is equal to the (…) magnitude of the stimulus producing sensation raised to a certain (…) which varies, depending on the sensation being measured.

A

magnitude, physical, power or expontent

56
Q

Top to bottom, spinal cord sections include: (…), (…), (…), (…), and (…). Damage to the (…) level results in quadriplegia or (…), while damage to the (…) causes paraplegia.

A

cervical, thoracic, lumbar, sacral, coccygeal, cervical, tetraplegia, thoracic

57
Q

Traditional antipsychotics are best for (…) symptoms of Schizophrenia. 3 side effects: (…), (…), (…). Block (…) receptors.

A

positive, anticholinergic, extrapyramidal effects, and neuroleptic malignant syndrome, dopamine

58
Q

An (…) (…) produces an effect opposite a neurotransmitter. (…) (…) similar but less than, and (…) produces no activity, but actually blocks the effect.

A

inverse agonist, partial agonist, antagonist

59
Q

Hyperthyroidism is caused the (…) of (…) by the thyroid gland, characterized by increased metabolism, elevated temperature, accelerated (…) rate, increased (…) with weight loss, (…), and insomnia.

A

hypersecretion, thyroxine, heart, appetite, nervousness

60
Q

Hyporthyroidism is caused the (…) of (…) by the thyroid gland, characterized by slowed metabolism, lowered temperature, slowed (…) rate, (…), impaired concentration and (…), and depression.

A

hyposecretion, thyroxine, heart, lethargy, memory

61
Q

Methylphenidate (e.g. (…)) is a psychostimulant used to treat (…), side effects: decreased (…), insomnia, (…), and growth (…).

A

Ritalin, ADHD, appetite, dysphoria, suppression

62
Q

Action Potential: Neuron becomes (…), interior cell less negative, triggering an electrical impulse. All-or-none, AP will be same (…) regardless of amount of (…) as long as minimal (…) has been reached.

A

depolarized, magnitude, stimulation, threshold

63
Q

The (…) (…) system is a network of nerve fibers involved in (…), arousal, and (…).

A

reticular activating, wakefulness, consciousness

64
Q

SSRIs (e.g. (…)) (…) the reuptake of serotonin. Side effects: GI disturbance, (…) dysfunction, insomnia, (…), headache, and (…). VS TCAs, they are less (…), safer in overdose, and less (…) impairments.

A

Fluoxetine, block, sexual, anxiety, anorexia, cardiotoxic, cognitive

65
Q

There are 3 sedative-hypnotics: (…), (…), and alcohol. They are (…) depressants. Low dose reduce arousal and motor activity, moderate sleep, high anesthesia and death.

A

barbiturates, anxiolytics, CNS

66
Q

Benzo’s are a type of (…), side effects: drowsiness, (…), slurred speech, (…), and impaired (…) ability; abrupt cessation can cause (…) hyperexcitability.

A

anxiolytic, ataxia, lethargy, psychomotor, rebound

67
Q

4 Neurotransmitters: (…). They are (…) substances released from axon (…), diffuse across (…), and (…) or (…) receptor sites on postsynaptic nerve cells.

A

Acetylcholine, Dopamine, Serotonin, and Gaba; chemical, terminals, synapses, excite or inhibit

68
Q

Acetylcholine mediates (…) transmission, (…) arousal, and (…). Dopamine is involved in (…) motor regulation and (…)/(…) functions. Too little in (…), Parkinson’s, too much and you get Schizophrenia and (…) Disorder.

A

neuromuscular, parasympathetic, memory; inhibitory, motivational/emotional, basal ganglia, Tourette’s

69
Q

Serotonin (…) behavior, regulates mood, (…), arousal, (…), temperature, and (…). GABA most common (…) neurotransmitter, involved in (…), sleep, and (…). Too low and you get (…) Disease.

A

inhibits, hunger, sleep, pain; inhibitory, anxiety, seizures, Huntington’s

70
Q

Migraine headache is a recurrent (…) headache, with (…) pain usually on one side of head. Triggers: alcohol, (…), and (…) following stress. May be preceded by (…) (classic migraine).

A

vascular, throbbing, bright lights, relaxation, aura

71
Q

Mood stabilizers treat symptoms of (…) Disorder. Common are (…) and (…). For traditional BD, (…) is used. Rapid mood swings or dysphoric mania, use (…).

A

Bipolar, lithium and anticonvulsants, lithium and anticonvulsants,

72
Q

(…) Effects are caused by several drugs including (…) and tricyclic antidepressants. They include: (…) mouth, (…) vision, tachycardia, (…) retention, constipation, memory impairment and (…).

A

Anticholinergic, antipsychotics, dry, blurred, urinary, confusion

73
Q

Tricyclics include (…) and (…). They block the reuptake of (…), (…), and (…). Most effective for (…), (…) symptoms. Side Effects: (…) effects, confusion, weight gain, and (…) symptoms. (…) good for enuresis, (…) for Panic, Bulimia, and (…).

A

Imipramine and Clomipramine, norepinephrine, serotonin, dopamine, somatic, vegetative, anticholinergic, cardiovascular, imipramine, clomipramine, OCD

74
Q

Brain Lateralization: LEFT: (…) activities, (…) thought, and (…) emotions. RIGHT: (…)-(…) activities, (…) interpretation, and memory for (…), and (…) emotions.

A

verbal, analytical/logical, positive; visual-spatial, spatial, shapes, negative;

75
Q

Split Brain Patient: A familiar object presented to (…) visual field, can name the object but cannot pick it out with his (…) hand.

A

right, left

76
Q

Split Brain: Presented the word “headband” straight ahead, will report seeing: (…).

A

“band” (why - verbally state what perceived by left hemisphere, what was in her right visual field)

77
Q

Front Cortex includes: (…), (…), (…), (…), and prefrontal cortex. It’s involved in (…) functioning, (…) and mood, and (…) functions.

A

primary motor cortex, supplementary motor area, premotor cortex, Broca’s Area; executive, personality, motor

78
Q

TBI includes both (…) and (…) injuries. The first causes alteration or (…), followed by (…) and (…) amnesia. The later affects (…) versus (…) memories. (…) memories return first.

A

closed-head and open-head, LOC, anterograde and retrograde, recent versus remote, remote

79
Q

(…) is the inability to differentiate between different hues.

A

achromatopsia

80
Q

The three brain structures involved in implicit memory are: (…), (…), and (…).

A

cerebellum, basal ganglia, and amygdala

81
Q

(…) is a hormone released by the (…) cortex and plays a role in sexual arousal for men and women.

A

androgen, adrenal

82
Q

Neurogenis, the creation of new neurons, occurs in the (…) throughout the lifespan.

A

hippocampus