Physical Basis of Heredity - Handout Flashcards

1
Q

Actively dividing eukaryote cells pass through a series of stages known collectively as the

A

cell cycle

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2
Q

cell double checks the duplicated chromosomes for error, making any needed repairs

A

G2

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3
Q

each of the 46 chromosomes is duplicated by the cell

A

s phase

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4
Q

cellular contents, excluding the chromosomes, are duplicate

A

G1

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5
Q

Metabolic changes prepare the cell for division. At a certain point - the restriction
point - the cell is committed to division and moves into the S phase

A

G1 phase

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6
Q

DNA synthesis replicates the genetic material. Each chromosome now consists of
two sister chromatids

A

s phase

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7
Q

. Metabolic changes assemble the cytoplasmic materials necessary for mitosis and
cytokinesis.

A

g2 phase

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8
Q

e. A nuclear division (mitosis) followed by a cell division (cytokinesis)

A

m phase

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9
Q

s is a form of eukaryotic cell division that produces two daughter cells with the same
genetic component as the parent cell

A

mitosis

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10
Q

Chromosomes replicated during the S phase are divided
in such a way as to ensure that each daughter cell receives a copy of every chromosome. In
actively dividing animal cells, the whole process takes about

A

one hour

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11
Q

The replicated chromosomes are attached to a

A

mitotic apparatus

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12
Q

’ that aligns them and then
separates the sister chromatids to produce an even partitioning of the genetic material

A

mitotic apparatus

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13
Q

separation of the genetic material in a mitotic nuclear division

A

karyokinesis

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14
Q

separation of the cell cytoplasm in a cellular division

A

cytokinesis

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15
Q

In some single-celled organisms mitosis forms the basis of a

A

asexual reproduction

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16
Q

In diploid
multicellular organisms sexual reproduction involves the fusion of two __ gametes to produce a diploid zygote

A

haploid

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17
Q

five stages of mitosis

A

prophase
prometaphase
metaphase
anaphase
telophase

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18
Q

occupies over half of mitosis. The nuclear membrane breaks down to form a
number of small vesicles and the nucleolus disintegrates

A

prophase

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19
Q

structure known as the
___ duplicates itself to form two daughter centrosomes that migrate to opposite ends
of the cell. T

A

centrosome

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20
Q

. The centrosomes organise the production of microtubules that form the spindle
fibres that constitute the

A

mitotic spindle

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21
Q

s. Each replicated chromosome can now be seen to consist of two identical

A

chromatids

22
Q

Each replicated chromosome can now be seen to consist of two identical
chromatids (or sister chromatids) held together by a structure known as the

A

centromere

23
Q

The chromosomes, led by their centromeres, migrate to the ___ plane in the midline of
cell - at right-angles to the axis formed by the centrosomes

A

equatorial plate

24
Q

The chromosomes, led by their centromeres, migrate to the equatorial plane in the midline of
cell - at right-angles to the axis formed by the centrosomes. This region of the mitotic spindle
is known as the

A

metaphase plate

25
The spindle fibres bind to a structure associated with the centromere of each chromosome called a
kinetochore
26
The chromosomes align themselves along the metaphase plate of the spindle apparatus.
metaphase
27
The shortest stage of mitosis.
anaphase
28
s. The centromeres divide, and the sister chromatids of each chromosome are pulled apart - or 'disjoin' - and move to the opposite ends of the cell, pulled by spindle fibres attached to the kinetochore regions. The separated sister chromatids are now referred to as
daughter chromosomes
29
The final stage of mitosis, and a reversal of many of the processes observed during prophase.
telophase
30
The final cellular division to form two new cells
cytokinesis
31
in plants, this forms during cytokinesis
cell plate
32
in animals, this form along the line of metaphase plate in cytokinessi
constriction of cytoplasm
33
s is the form of eukaryotic cell division that produces haploid sex cells or gametes
meiosis
34
a special cell division reduces the cell from diploid to haploid.
meiosis I
35
The homologous chromosomes pair and exchange DNA to form recombinant chromosomes. what stage in meiosis
prophase I
36
Prophase I is divided into five phases:
leptotene zygotene pachytene diplotene diakinesis
37
chromosomes start to condense what stage of prophase I
leptotene
38
homologous chromosomes become closely associated (synapsis) to form pairs of chromosomes (bivalents) consisting of four chromatids (tetrads). what stage in prophase I
zygotene
39
pairs of chromosomes in zygotene
bivalents
40
crossing over between pairs of homologous chromosomes to form chiasmata (sing. chiasma). what phase in prophase I
pachytene
41
homologous chromosomes start to separate but remain attached by chiasmata
diplotene
42
s: homologous chromosomes continue to separate, and chiasmata move to the ends of the chromosomes.
diakinesis
43
Spindle apparatus formed, and chromosomes attached to spindle fibres by kinetochores. stage of meiosis I
prometaphase I
44
Homologous pairs of chromosomes (bivalents) arranged as a double row along the metaphase plate. The arrangement of the paired chromosomes with respect to the poles of the spindle apparatus is random along the metaphase plate.
metaphase I
45
This is a source of genetic variation through random assortment, as the paternal and maternal chromosomes in a homologous pair are similar but not identical
metaphase I
46
The number of possible arrangements is 2n, where n is the number of chromosomes in a haploid set. Human beings have 23 different chromosomes, so the number of possible combinations is
223
47
The homologous chromosomes in each bivalent are separated and move to the opposite poles of the cell.
anaphse I
48
The chromosomes become diffuse and the nuclear membrane reforms. what phase in meiosis I
telophase
49
The final cellular division to form two new cells, followed by Meiosis II. M
cytokinesis
50
Meiosis generates genetic diversity through (3)
the exchange of genetic material between homologous chromosomes during Meiosis I (pachytene) the random alignment of maternal and paternal chromosomes in Meiosis I (metaphase I) the random alignment of the sister chromatids at Meiosis II
51
what stage of Meiosis I does the first polar body form
teloophase I
52
which stage of Meiosis II does the egg cell turn into polar body and mature egg cell
cytokinesis