Physical Basis of Heredity - Handout Flashcards
Actively dividing eukaryote cells pass through a series of stages known collectively as the
cell cycle
cell double checks the duplicated chromosomes for error, making any needed repairs
G2
each of the 46 chromosomes is duplicated by the cell
s phase
cellular contents, excluding the chromosomes, are duplicate
G1
Metabolic changes prepare the cell for division. At a certain point - the restriction
point - the cell is committed to division and moves into the S phase
G1 phase
DNA synthesis replicates the genetic material. Each chromosome now consists of
two sister chromatids
s phase
. Metabolic changes assemble the cytoplasmic materials necessary for mitosis and
cytokinesis.
g2 phase
e. A nuclear division (mitosis) followed by a cell division (cytokinesis)
m phase
s is a form of eukaryotic cell division that produces two daughter cells with the same
genetic component as the parent cell
mitosis
Chromosomes replicated during the S phase are divided
in such a way as to ensure that each daughter cell receives a copy of every chromosome. In
actively dividing animal cells, the whole process takes about
one hour
The replicated chromosomes are attached to a
mitotic apparatus
’ that aligns them and then
separates the sister chromatids to produce an even partitioning of the genetic material
mitotic apparatus
separation of the genetic material in a mitotic nuclear division
karyokinesis
separation of the cell cytoplasm in a cellular division
cytokinesis
In some single-celled organisms mitosis forms the basis of a
asexual reproduction
In diploid
multicellular organisms sexual reproduction involves the fusion of two __ gametes to produce a diploid zygote
haploid
five stages of mitosis
prophase
prometaphase
metaphase
anaphase
telophase
occupies over half of mitosis. The nuclear membrane breaks down to form a
number of small vesicles and the nucleolus disintegrates
prophase
structure known as the
___ duplicates itself to form two daughter centrosomes that migrate to opposite ends
of the cell. T
centrosome
. The centrosomes organise the production of microtubules that form the spindle
fibres that constitute the
mitotic spindle
s. Each replicated chromosome can now be seen to consist of two identical
chromatids
Each replicated chromosome can now be seen to consist of two identical
chromatids (or sister chromatids) held together by a structure known as the
centromere
The chromosomes, led by their centromeres, migrate to the ___ plane in the midline of
cell - at right-angles to the axis formed by the centrosomes
equatorial plate
The chromosomes, led by their centromeres, migrate to the equatorial plane in the midline of
cell - at right-angles to the axis formed by the centrosomes. This region of the mitotic spindle
is known as the
metaphase plate