Genetics: Definition, Application, and History Flashcards
alteration in the DNA sequences; causes DNA variation
mutation
study of heredity and variation
genetics
who coined the term genetics
William Bateson
GEN means
beginning
GEN means beginning in what language
Greek
is the father of modern medicine
Hippocrates
is the father of biology
Aristotle
title of Charles Darwin’s book
Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life
suggesting that every part of the body produces tiny particles called “gemmules” which travel to the reproductive cells and are passed on to offspring
theory of pangenesis
tiny particles of the body that travel to the reproductive cells and are passed to offsprings (developed by Charles Darwin)
gemmules
theory of pangenesis is developed by
Charles Darwin
- states that only the genetic material in the germ cells (sex cells) is passed on to offspring, rejecting the idea that changes in the body during an organism’s life can be inherited (contradicting the concept of pangenesis).
germplasm theory
who developed the Germplasm theory
August Weissman
developed the theory of inheritance of acquired characteristics
Jean Baptiste de Lamarck
- Hereditary characteristics are determined by elementary unit Mendelian Factor (GENES) transmitted between generation in uniform predictable fashion
developed by who
Gregor Mendel
- is the study of how genes are passed down from parents to their offspring
transmission genetics
- is the combination of traits that make up a person’s personality
character
a single characteristic or quality
contrasting trait
control unit of the cell
nucleus
hereditary material resides in the nucleus
stated by who
Ernst Haeckel
genetic material of eukaryotes
DNA
genetic material of bacteria
DNA
genetic bacteria of viruses
DNA or RNA
a single chromatid is called this
chromatid
sister chromatids; chromosome
dyad
similar but not identical
homologous chromosomes
- One of the pair contains paternally-derived alleles and other contains maternally-derived alleles
homologous chromosomes
a human has how many chromosomes
2n = 46
1 -22 chromosomes
autosomes
23 chromosomes
sex cells
male
XY
female
XX
is a test that examines chromosomes in cells to identify genetic disorders. It’s important because it can help diagnose genetic diseases, birth defects, and blood disorders.
karyotyping
is a genetic condition caused by an extra chromosome
trisomy 21
– short arm, comes from the French word petit means “small
petite
long arm, since it is after the p arm
q arm
chromosomal theory of inheritance
Walter Sutton and Theodor Boveri
states that genes are located on chromosomes, and the behavior of these chromosomes during meiosis explains how traits are inherited from parents to offspring,
chromosomal theory of inheritance
coined Genetics, Homozygote, Hereozygote, Epistasis
William Bateson
An organism that has identical copies of a gene, or alleles, for a specific trait.
Homozygote
- An organism that has different copies of a gene, or alleles, for a specific trait.
heterozygote
- a genetic phenomenon where the expression of one gene is affected by the expression of other genes
epistasis
- is a gene variant that is expressed when present in an organism
dominant gene
– is a section of DNA that has a low chance of being expressed in an organism
recessive gene
first filial generation
f1
second filial generation
F2
set of observable characteristics of an individual resulting from the interaction of its genotype
phenotype
lethal genes are ___ genes
dominant
– father of modern genetics
thomas hunt morgan
chromosomes fail to separate during cell division
non disjunction
- are nucleic acids (RNA) that have been shown to have catalytic ability, which means they can act as enzymes.
ribozymes
chargaff rules state
the amount of adenine (A) is equal to that of thymine (T) and the amount of guanine is equal to that of cytosine (C) in an organism.
- DNA is negatively charged due to
phosphate
is also called as transcription
RNA synthesis
is also called as translation
protein synthesis
DNA synthesis is called
replication
nucleoside with additional phosphate groups
nucleotide
is made up of a nitrogenous base and a five-carbon sugar, like ribose
nucleoside
segment of DNA or RNA that contains instructions for making proteins
genes
Archaea is closer to what domain
Eukarya
three great milestone in genetics
Gregor mendel rules of inheritance
francis Crick model for DNA structure
human genome project
is the study of heredity and variation
genetics
means to become or to grow
GEN
stated that hereditary material resides in the nucleus
Ernst Haeckel
successfully isolated nuclein from pus cells obtained from discarded bandages
Johann Friedrich Miescher
stated that chromosomes are condensed form of material found in the nucleus
Wilhem von Waldeyer
stated that specific chromosomes are responsible for determining sex in animals
clarence erwin mcclung
develoepd the concept of linkage and modifier genes
william bateson
reginald punnett
application of genetics
plant and animal improvement
medicine
genetic counseling
legal applications
genetic engineering