Phys 4 Flashcards
What is the major mxn for uptake of protein and fats into the enterocytes?
pinocytosis
What are the layers to go from the lumen to the blood?
unstirred layer of fluid –> glycocalyx –> apical membrane
–> cytoplasm of cell –> basolateral membrane –> basement membrane –> wall of capillary or lymph vessel
Maltose
maltose–> glucose and glucose
Trehalose
trehalase –> glucose and glucose
Lactose
lactase–> glucose and galactose
Sucrose
sucrase–> glucose and fructose
Starch
alpha amylase –> alpha dextrin -alpha dextrinase-> glucose
alpha amylase –> maltose -maltase-> glucose
alpha amylase –> maltotriose -sucrase-> glucose
CHO Testing
a. D-xylose levels above 4 g: you’re good
b. D-xylose levels below 4 g: you have an absorption problem
*urine collected continuously over 5 hours
What are the endopeptidases we learned?
trypsin, pepsin, chymotrypsin, elastase –> make small polypeptides
What are the exopeptidase we learned?
carboxypeptidases A and B –> cleaves AA into carboxyl ends
What ion is associated with AA take up? di/tri peptides?
- Na+
- H+
- each type of AA has it’s own transporter
- *Na/K establishes Na+ gradient
What can CF lead to protein absorption problems?
CFTR is blocked, so Cl- isn’t gonna want to go into the cell, which means the transporter with HCO3- isn’t doing too hot… can lead to pancreatitis, and an inflamed pancreas isn’t gonna wanna make all them enzymes we need
*steatorrhea think CF
Triglyceride
—-lingual, gastric, pancreatic lipase—> monoglyceride + FA + FA
Cholesterol ester
—cholesterol ester hydrolase–> cholesterol + FA
Phospholipid
–phospholipase A2—> lysolecithin + FA
