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GI 2 > Important Channels > Flashcards

Important Channels Flashcards

1
Q

MRP2

A

BA from hepatocyte to bile canaliculi for biliary excretion

*mutations lead to Dubin Johnson

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2
Q

ASBT

A

BA into lumen of enterocyte

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3
Q

OST alpha/beta

A

BA from enterocyte to portal circulation

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4
Q

NTCP

A

BA from portal circulation to hepatocyte

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5
Q

BSEP

A

BA from hepatocyte to bile canaliculi for biliary excretion

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6
Q

OATP1B1/OATPB3

A

mutations in these transporters cause Rotor’s syndrome

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GI 2 (10 decks)

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