Phylum Sarcomastigophora Flashcards
What is the common name of the Subphylum Mastigophora?
The Flagellates –> flagella present in trophozoites
What are the main features of Family Trypanosomatidae?
Require an IH - arthropods
Cause death in humans and animals
Extracellular and intracellular location
Genus Trypanosoma
Genus Leishmania
Spindle shaped body One flagellum Underlating membrane Contains a kinetoplast Many phases of development Many species change the body form depending on the host and organ in which they are located
what are the main features of Genus Trypanosoma?
Widespread in the trypomastigote form
Live in blood and tissues
Binary fission
All species except T. equiperdum are transmitted by vectors
Contain 2 groups
- Salivaria: within anterior part of GIT (salivary glands of vector)
- Stercoraria: within posterior part of vector - faecal contamination
What are the features of Trypanosoma - Group Salivaria
Spindle shape
Blunt posterior end
Kinetoplast in terminal position
Free flagellum at anterior end can be present
What are the features of Trypanosoma - Group Stercoaria
Free flagellum always present
Posterior end is pointed
Kinetoplast is subterminal
What are the general features of Trypanosoma evansi / brusei?
Cause Sura disease
Within horses, donkey,s mules, deer, camels, Llamas, dogs, cats
Posterior end is thin, free flagellum and underlating membrane
Located in the circulation
Transmitted by Tabanus spp of fly (no development) –> very painful as it is not easy to get blood from host –> will cause pain and receive a small amount of blood before moving to another host and infecting them
What are the general features of Trypansoma equiperdum?
Affects horses, donkeys and mules
Not in Aus
Transmitted via sex (venereally)
Causes acute or chronic illness
What are the general features of Trypansoma brucei?
T. b. brucei
T. b. gambiense
T. b. rhodesiense
Transmitted by Glossina species –> development within fly)
What are the general features of the subspecies Trypansoma brucei brucei?
Not within humans
Pathology in many species including horses and cattle
Contain 2 forms - 1 in host and 1 in fly
many hosts
Trypomastigote is within blood of the host
Invades the cerebrospinal fluid
In the vertebrate –> trophomastigote
In the vector –> epimastigote
Transmission via flies
Which species of Trypansoma causes African Sleeping sickness?
Trypansoma brucei gambiense
Trypanosoma brucei rhodesiense
What is the main features of Genus Leishmania?
Within in tropical, subtropical and temperate areas (Not Aus)
Causes severe disease in humans and animals
Transmitted via the bite of female sandflies
Zoonotic
More than 14 species can infect humans and cause:
- Visceral disease
- Cutaneous disease
- Musculo-cutaneous disease
Within dogs –> can cause visceral and cutaneous disease (L. infantum)
Have 2 forms:
- Amastigotes –> mammals and in macrophages. Contain a rudimentary flagellum that does not project beyond the body –> not motile
- Promastigote –> in sandflies, have motility and working flagellum.
What is the lifecycle of Genus Leishmania?
When feeding on an infected host, the female sandfly will ingest macrophages
Amastigotes within the macrophages that have been ingested by the female sandfly form into promastigotes, they divide by binary fission and then when the female sandfly feeds, will transfer into the host.
Promastigotes are then released into the blood of the host and are phagocytised by macrophages –> form into Amastigotes and divide in the host cells –> amastigotes will burst the cell, release into blood and invade other cells.
What cases of Leishmania in Australia have been seen?
In 2004, Kangaroos in the NT contained skin lesions on the ears, tail and limbs, the Leishmania species was identified.
What are the general features of Order Trichomonadida?
Flagellate protozoa that inhibit the alimentary canal / urogenial system of vertebrates and invertebrates
Contain an undulating membrane and is bordered by a flagellum
Body is pyriform (rounded anterior and pointed posterior end)
One nucleus
3-5 anterior flagella and a posterior or recurrent flagellum which is incorporated into the undulating membrane
Contains a free flagellum
Reproduce via binary fission
What is the main features of Trichomonas gallinae?
Host - birds, mainly from Columbiformes (pigeons and doves) as well as budgies, hawks, eagles, chickens, etc.
Located in the Digestive tract, mouth, pharynx, oesophagus and crop
Adult pigeons are asymptomatic carriers
Young pigeons are symptomatic, degeneration in oral and nasal cavities
Contain 4 anterior flagella, no free posterior flagellum.
Undulating membrane does not reach posterior end of body
Parasites develop in the mouth and block the feeding and airway –> young birds will die, if they survive, will become carriers