phases of Gastric secretion Flashcards

1
Q

Gastric secretion occurs in 3 phases

A

Cephalic phase
Gastric phase
Intestinal phase

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2
Q

This phase occurs even before the food enters the stomach

A

Cephalic phase

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3
Q

The cephalic phase results from what?

A

smell
sight
thought
taste

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4
Q

appetite and stimulation relation

A

greater appetite, intense stimulation

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5
Q

Neurogenic signals originate in _________.

A

cerebral cortex and appetite centers of amygdala and hypothalamus

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6
Q

How are neurogenic signals from the cerebral cortex and appetite centers of the amygdala and hypothalamus transmitted?

A

dorsal motor nuclei of vagi —> vagus nerve –> stomach

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7
Q

The cephalic phase accounts for _____ of the gastric secretion associated with a meal

A

30%

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8
Q

This phase occurs when food enters the stomach

A

Gastric phase

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9
Q

When food enters the stomach, the following are excited:

A
  • local nervous secretory reflex
  • Vagal reflex
  • Gastrin-histamine stimulation
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10
Q

Gastric secretions account for ______ of gastric acid secretion

A

60%

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11
Q

Occurs once the food is in the proximal small intestine

A

Intestinal phase

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12
Q

continuous small amounts of stomach secretion are partly due to _________.

A

gastrin released by duodenal mucosa

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13
Q

Intestinal phase accounts for _____ of the gastric acid

A

10%

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14
Q

Possible causes of Inhibition of gastric secretion

A
  • presence of food in the small intestine
  • the presence of food end-products, osmotic fluid, irritation
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15
Q

reflex initiated by the presence of food in the small intestine

A

reverse enterogastric reflex

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16
Q

What is the reverse enterogastric reflex?

A

slows gastric emptying upon small intestine filling

17
Q

reverse enterogastric reflex is triggered by:

A
  • distension of small bowel
  • presence of acid in the upper intestine
  • presence of protein breakdown products
  • mucosal irritation
18
Q

the presence of food end-products, osmotic fluid, and irritation causes the release of which hormone?

A

secretin
- glucose-dependent insulinotropic peptide
- vasoactive intestinal peptide
- somatostatin

19
Q

secretin is important for?

A

pancreatic secretion

20
Q

What does Secretin oppose?

A

gastric secretion

21
Q

What is interdigestive state?

A

small amounts of gastric juice are secreted even with little to no digestion occurring

22
Q

Interdigestive state secretion content

A
  • mainly mucus
  • no Acid
  • a small amount of pepsin
23
Q

Stimuli that can increase inter-digestive secretion

A

Emotional stimuli

24
Q

Emotional stimuli increase interdigestive secretion to _______________.

A

> or = to 50 mL/hr, mostly peptic/acidic
- similar to cephalic phase

25
Q

An increase in inter-digestive secretion may contribute to ___________________ (condition) development.

A

peptic ulcer

26
Q

Terminal 5 amino acids of these are essential

A

Gastrin and CCK

27
Q

Terminal 4 amino acids are essential

A

Gastrin’s (functional) activity

28
Q

All of the amino acids here are essential

A

Secretin

29
Q

Terminal eight amino acids are essential

A

CCK activity