Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

TMD > Pharmacotherapy > Flashcards

Pharmacotherapy Flashcards

1
Q

For the reduction of pain to promote function.

A

Pharmacotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Analgesics include:

A
  • NSAIDs
  • Acetaminophen
  • Corticosteroids
  • Injections (LA)
  • Opioids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

These suppress the action of prostaglandins and thromboxanes by inhibiting cyclooxygenases.

A

NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Effects of NSAIDs.

A
  • Analgesic
  • Anti-inflammatory
  • Anti-pyretic
  • Anti-coagulant
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Selective NSAIDs inhibit…

A

COX-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Non-selective NSAIDs inhibit…

A

COX 1 and 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

A type of NSAID that’s called Advil

A

Ibuprofen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

These are used for mild to moderate pain, or post-surgical pain.

A

NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

NSAIDs cannot be used in these patients:

A
  • Renal disease
  • Asthma
  • GI ulcers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Avoid these COX inhibitors if there’s an allergy to sulfa meds.

A

2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

AKA Tylenol

A

Acetaminophen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The drug of choice for pregnancy.

A

Acetaminophen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tylenol MOA

A

Inhibits COX-3, which acts in the CNS.

Does NOT suppress prostaglandins!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Acetaminophen max dose.

A

3g/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Avoid use of Acetaminophen in:

A
  • Liver disease

- Chronic alcoholics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

These prevent the breakdown of cell mediators.

A

Corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

These are for moderate to severe pain, and TMJ SURGERY.

A

Corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How do you discontinue corticosteroids?

A

Taper the dose.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Where do corticosteroids work?

A

Peripherally at the tissue level.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

These block voltage-gated Na channels on nociceptors.

A

Local anesthetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Long-acting LA.

A

Bupivacaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Avoid LA’s in what?

A

Myositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

These act at nociceptors.

A

LA’s

Opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Act on Mu, Kappa, and Delta receptors.

A

Opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Do not give this drug to someone with chronic pain, bc it can cause dependence.

A

Opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

These drugs act on peripheral and central nociceptors.

27
Q

Adjunct analgesics

A
  • Muscle relaxants
  • Anxiolytics - Benzodiazepines
  • Antidepressants (TCA’s)
  • NMDA Receptor Antagonist
28
Q

Where do adjunct analgesics act?

29
Q

These are not designed to control pain.

A

Adjunct analgesics

30
Q

Common muscle relaxants.

A
  • Baclofen
  • Tizanidine
  • Cyclobenzaprine
31
Q

Clinical uses of muscle relaxants.

A
  • Masticatory muscle pain
  • Muscle pain upon awakening
  • Sleep disturbance associated with pain
32
Q

These drugs act at the tissue level.

A

NSAIDS

Steroids

33
Q

These drugs act centrally

A

Muscle relaxants
Acetaminophen
Opioids

34
Q

Muscle relaxants act centrally or peripherally.

35
Q

Benzos cause the release of what?

36
Q

Function of GABA

A

Inhibit the motor endplate to cause muscle relaxation.

37
Q

Benzos end in what?

A

“azepam”

38
Q

Benzos may worsen this.

A

Depression

39
Q

These are given for chronic pain with sleep disturbances.

A

Tricyclic antidepressants

40
Q

Tricyclic antidepressants MOA

A

Inhibit the reuptake of Serotonin and NE.

41
Q

Increase the inhibitory descending bulbospinal pathway.

42
Q

These drugs are used for chronic pain.

A

NMDA receptor antagonists

43
Q

Examples of NMDA receptor antagonsits.

A

Ketamine

Dextromorphan

44
Q

You need 2400 mg/day of this drug in order to have anti-inflammatory effects.

A lower does only has anti-analgesic effects.

45
Q

Pain from injury or disease to the nervous system (PNS and CNS).

A

Neuropathic pain

46
Q

Classifications of neuropathic pain.

A

1) Continuous

2) Episodic

47
Q

Meds used for neuropathic pain.

A

Anticonvulsants & Capsaicin

48
Q

Anticonvulsants

A

Carbamazepine
Oxaycarmazepine
Gabapentin
Pregabalin

49
Q

Anticonvulsant that decreases the conductance of Na and K, suppressing alpha delta and C fibers.

A

Carbamazepine

50
Q

Blocks voltage-gated Na and Ca channels.

A

Oxycarbazepine

51
Q

Anticonvulsant that affects voltage gated Ca channels, but the mechanism is uncertain.

A

Gabapentin

52
Q

Anticonvulsant that’s similar in effect to gabapentin, binds to a subunit of Calcium channel and reduces neuronal activity.

A

Pregabalin

53
Q

Activation of this receptor destroys nociceptive fibers.

54
Q

This drug activates the TRPV1 Receptor.

55
Q

This drug is used as/for:

  • Diagnostic aid
  • Burning Mouth
  • Atypical odontalgia
56
Q

Avoid this NSAID in asthma patients.

57
Q

Avoid this drug if have a sulfa allergy.

58
Q

This NSAID is for MODERATE pain intensity.

A

Acetaminophen

59
Q

This drug is contraindicated for osteoporosis.

A

Methyl prednisone (osteoporosis)

60
Q

Avoid this in gastric ulcer.

61
Q

Avoid this in hypercholesterolemia.

62
Q

Used for inflamation and severe pain.

A

Methyl Prednisone

63
Q

Avoid this type of drug if have gastric ulcers.

64
Q

This drug is for CHRONIC pain

A

.Amitriptyline (Tricyclic Antidepressants)

TMD (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions