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USLME Step 1 > Pharmacology- First Aid > Flashcards

Pharmacology- First Aid Flashcards

1
Q

Drug Reactions- Coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids

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2
Q

Drug Reactions- Cutaneous flushing

A

vancomycin, adenosine, niacin, Ca channel blockers

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3
Q

Drug Reactions- dilated cardiomyopathy

A

doxorubicin, daunorubicin

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4
Q

Drug Reactions- torsades de pointes

A

Class III and Ia antiarrhythmics, macrolides, antipsychotics, TCA’s

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5
Q

Drug Reactions- hot flashes

A

tamoxifen, clomiphene

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6
Q

Drug Reactions- hyperglycemia

A

tacrolimus, protease inhibitors, niacin, HCTZ, beta blockers, corticosteroids

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7
Q

Drug Reactions- hypothyroidism

A

lithium, amiodarone, sulfonamides

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8
Q

Drug Reactions- acute cholestatic hepatitis, jaundice

A

erythromycin

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9
Q

Drug Reactions- diarrhea

A

metformin, erythromycin, colchicine, orlistat, acarbose

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10
Q

Drug Reactions- focal to massive hepatic necrosis

A

halothane, amanita phalloides, valproic acid, acetaminophen

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11
Q

Drug Reactions- hepatitis

A

INH (isoniazid)

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12
Q

Drug Reactions- pancreatitis

A

didanosine, corticosteroids, alcohol, valproic acid, azathioprine, diuretics

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13
Q

Drug Reactions- pseudomembranous colitis

A

clindamycin, ampicillin, cephalosporins

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14
Q

Drug Reactions- agranulocytosis

A

dapsone, clozapine, carbamazepine, colchicine, methimazole, propylthiouracil

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15
Q

Drug Reactions- aplastic anemia

A

carbamazepine, methimazole, NSAIDS, benzene, chloramphenicol, PTU

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16
Q

Drug Reactions- direct coombs (positive hemolytic anemia)

A

methyldopa, penicillin

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17
Q

Drug Reactions- gray baby syndrome

A

chloramphenicol

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18
Q

Drug Reactions- hemolysis in G6PD deficiency

A

INH, sulfonamids, dapsone, primaquine, aspirin, ibuprofen, nitrofuratoin

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19
Q

Drug Reactions- megaloblastic anemia

A

phenytoin, methotrexate, sulfa drugs

20
Q

Drug Reactions- thrombocytopenia

A

heparin, cimetidine

21
Q

Drug Reactions- thrombotic complications

A

OCP’s

22
Q

Drug Reactions- fat redistribution

A

protease inhibitors, glucocorticoids

23
Q

Drug Reactions- gingival hyperplasia

A

phenytoin, verapamil, cyclosporine, nifedipine

24
Q

Drug Reactions- gout

A

pyrazinamid, thiazides, furosemide, niacin, cyclosporine

25
Q

Drug Reactions- myopathy

A

fibrates, niaicin, colchicine, hydroxychloroquine, interferon-alpha, penicillamine, statins, glucocorticoids

26
Q

Drug Reactions- osteoporosis

A

corticosteroids, heparin

27
Q

Drug Reactions- photosensitivity

A

sulfonamides, amiodarone, tetracyclines, 5-FU

28
Q

Drug Reactions- steven johnson’s

A

anti-epileptic drugs, allopurinol, sulfa drugs, penicillin

29
Q

Drug Reactions- SLE like

A

sulfa drugs, hydralazine, INH, procainamide, phenytoin, etanercept

30
Q

Drug Reactions- teeth discoloration

A

tetracycline

31
Q

Drug Reactions- tendon rupture

A

fluoroquinolones

32
Q

Drug Reactions- cinchonism

A

quinidine, quinine

33
Q

Drug Reactions- parkinson-like

A

antipsychotics, reserpine, metoclopramide

34
Q

Drug Reactions- seizures

A

INH, bupropion, imipenem/cilastatin, tramadol, enflurane, metoclopramide

35
Q

Drug Reactions- tardive dyskinesias

A

antipsychotics, metoclopramide

36
Q

Drug Reactions- diabetes insipidus

A

lithium, demeclocycline

37
Q

Drug Reactions- fanconi syndrome

A

expired tetracycline

38
Q

Drug Reactions- hemorrhagic cystitis

A

cyclophosphamide, ifosfamide

39
Q

Drug Reactions- interstitial nephritis

A

methicillin, NSAIDs, furosemide

40
Q

Drug Reactions- SIADH

A

carbamazepine, cyclophosphamide, SSRI’s

41
Q

Drug reactions- dry cough

A

ACE inhibitors (inhibit degradation of bradykinin which is a bronchial vasoconstrictor)

42
Q

Drug Reactions- pulmonary fibrosis

A

bleomycin, amiodarone, busulfan, methtrexate

43
Q

Drug Reactions- antimuscarinic

A

atropine, TCA’s, H1 blockers, antipsychotics

44
Q

Drug Reactions- disulfram

A

metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

45
Q

Drug Reactions- nephrotoxicity or ototoxicity

A

aminoglycosides, vancomycin, loop diuretics, cisplatin

USLME Step 1 (16 decks)

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