pharmacology: CNS drug list Flashcards
what are the sedative-hypnotics?
barbiturates, benzos, alcohol
what are the barbiturates? mechanism?
phenobarbital and thiopental
mechanism: prolong GABA activity by increasing duration of Cl- channel opening with GABA mimetic acitivity - binding site on GABA A complex
what are the benzos? mechanism?
alprazolam, diazepam, lorazepam, midazolam, temazepam, oxazepam
mechanism: potentiate GABA by increasing the frequency of Cl- channel opening (GABA A)
benzo antagonist
flumazenil
busipirone mechanism and use
5 HT1A partial agonist
used for generalized anxiety disorders
what are the anticonvulsants
carbamazepine, ethosuximide, valproic acid, phenytoin, diazepam, lorazepam, gabapentin
what drug is used in seizure states and neuropathic pain
gabapentin
what are the anesthetics (IV)
fentanyl, ketamine, midazolam, propofol, thipental
what are teh neuromuscular blocking agents
depolarizing: succinylcholine
nondepolarizing: atracurium, mivacurium, tubocurarine
what are the inhaled anesthetics?
halothane, nitrous oxide
what are the local anesthetics
lidocaine, bupivacaine, mepivacaine, procaine, cocaine
what are the opioid full agonists?
morphine, meperidine, methadone, fentanyl, heroine
what are the opioid partial agonists?
buprenorphine, codeine
what are the opioid mixed agonist=antagonists
nalbuphine
what are the opioid antagonists?
naloxone, naltrexone, methylnaltrexone
what are the typical antipsychotics?
chlorpromazine, fluphenazine, thioridazine, haloperidol
what are the atypical antipsychotics?
clozapine, risperidone, olanzapine, aripiprazole, quetiapine, ziprasidone
what are the antiparkinsonian drugs?
DA agonists, MAO-B inhibitor, AAAD inhibitor, M blockers, COMT inhibitor, DA release and M blocker
what are the DA agonists?
levodopa, bromocriptine, pramipexole
what is the MAO-B inhibitor?
selegiline
what is the AAAD inhibitor?
carbidopa
what is are the M blockers?
benztropine, trihexiphenidyl
what is the COMT inhibitor?
tolcapone
what is the DA releaser and M blocker
amantadine
