chromosomal translocations Flashcards by Abbey Phelps | Brainscape

Q

8;14

A

burkitt lymphoma c-myc activation

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Q

9;22

A

philadelphia chromosome CML - bcr-abl hybrid

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Q

11;14

A

mantle cell lymphoma - cyclin D1 activation

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Q

14;18

A

follicular lymphoma - BCL-2 activation

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Q

15;15

A

APL - M3 type of AML

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Q

what does APL respond to

A

all-trans retinoic acid

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Q

bcl-2 activation

A

14;18 - follicular lymphoma

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Q

cyclin D1 activation

A

11;14 - mantle cell lymphoma

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Q

BCR-ABL hybrid

A

CML 9;22

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Q

c-myc activation

A

8;14 burkitt lymphoma

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Q

where are the ig heavy chain genes?

A

chromosome 14 - constitutively expressed

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