path reproductive tumors

Question 1

ovarian tumor with call-exner bodies, increased estrogen, postmenopausal bleeding

Answer 1

granulosa cell tumor

Question 2

what is a call-exner body

Answer 2

granulosa cells arranged haphazardly around collections of eosinophilic fluid - resemble primordial follicle

Question 3

ovarian neoplasm - bilateral - psammoma bodies

Answer 3

serous cystadenocarcinoma

Question 4

ovarian - ;pseudomyxoma peritonei-intraperitoneal accumulation of muscinous material from ovary or appendiceal tumor

Answer 4

mucinous cystadenocarcinoma

Question 5

ovarian tumor most common in adolescents - equivalent to seminoma with sheets of uniform fried egg cells
tumor markers hCG and LDH

Answer 5

dysgerminoma

Question 6

ovarian tumor that is aggressive with yellow, friable (hemorrhagic) solid mass with schiller duval bodies
AFP tumor marker

Answer 6

yolk sac endodermal sinus tumor

Question 7

schiller-duval bodies

Answer 7

resemble glomeruli

Question 8

GI malignancy taht metastasizes to ovaries - mucin-secreting signet cell adenocarcinoma

Answer 8

Krukenberg tumor

Question 9

most common ovarian neoplasm with fallopian tube-like epithelium

Answer 9

serous cystadenoma

Question 10

multioculated, large, lined by mucus-secreting epithelium

Answer 10

mucinous cystadenoma

Question 11

loods like bladder that is yellow-tan and appears encapsulated with coffee bean nuclei on HE stain

Answer 11

brenner tumor

Question 12

bundles of spindle-shaped fibroblasts with meigs syndrome and “pulling” sensation in groin

Answer 12

fibroma

Question 13

meigs syndrome

Answer 13

triad of ovarian fibroma, ascites, hydrothorax

Question 14

abnormal uterine bleeding in postmenopausal woman - like granulosa cell tumor that may produce estrogen

Answer 14

thecoma

Question 15

painless, homogenous testicular enlargement with lobules with water cytoplasm and fried egg appearance
increased ALP

Answer 15

seminoma

Question 16

yellow, mucinous - aggressive testes tumor with schiller-duval bodies and increased AFP

Answer 16

yolk sac endodermal sinus tumor of testes

Question 17

increased hCG, disordered syncytiotrophoblastic and cytotrophoblastic with hematogenous metastases to lung and brain
-symptoms of hyperthyroid

Answer 17

choriocarcinoma

Question 18

hemorrhage mass with necrosis - painful
glandular/papillary morphology
increased hCG

Answer 18

embryonal carcinoma

Question 19

golden brown color in testicle - reinke crystals that produces androgens or estrogens

Answer 19

leydig cell

Question 20

androblastoma from sex cord stroma

Answer 20

sertoli cell tumor

Question 21

most common testicular cancer in OLDER men

Answer 21

testicular lymphoma

Question 22

CA-125

Answer 22

epithelial carcinomas of the ovary (serous, endometriod, clear cell)

Question 23

epithelial tumors ovary

Answer 23

serous and mucinous cystadenocarcinoma

Question 24

germ cell tumors ovary

Answer 24

dysgerminoma and yolk sac

Question 25

sex cord stroma tumors ovary

Answer 25

sertoli-leydig and granulosa cell