Pharmacology Flashcards
1
Q
Common drugs affected by CYP3A4
A
VCR and fluconazole
2
Q
DLT of carboplatin
A
thrombocytopenia DLT
3
Q
DLT of cisplatin
A
peripheral neuropathy DLT
4
Q
Pulmonary fibrosis from an alkylator
A
busulfan and carmustine (BCNU)
5
Q
Irinotecan glucuronidator
A
UGT1T1
6
Q
Lab abnormalities with isotretinoin
A
hypercalcemia and hypertriglyceridemia
7
Q
Cabozantinib unique SE
A
pneumothorax SE
8
Q
Sunitinib unique SE
A
cardiac dysfunction SE
9
Q
Vandetanib unique SE
A
prolonged QTc SE
10
Q
Entrectinib unique SE
A
weight gain, ataxia, and bone fractures
