Pharmacogenetucs Flashcards

1
Q

What factors influence drug response phenotype ?

A
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2
Q

What are the genetics variations that interfere with pharmacogenetics?

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3
Q

What are the types of genetic variations ?

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4
Q

What variations in enzymes can affect drug metabolism?

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5
Q

Describe N acetyltransferase 2 polymorphism

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6
Q

What are the examples of N-acetyltransferase 2 polymorphisms?

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7
Q

What is Butyrylcholinesterase polymorphism?

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8
Q

What is a CYP2D6 polymorphism?

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9
Q

What is the consequence of CYP2D6?

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10
Q

What is thiopurine S-methyltransferase polymorphism ?

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11
Q

How can thiopurine s-methyltransferase?

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12
Q

What are the multiple genes of thiopurine s-methyl transferase polymorphism?

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13
Q

What are the genetic variations associated with thiopurine s methyltransferase?

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14
Q

What’s the impact of G6P deficiency?

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15
Q

What is malignant hyperthermia?

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16
Q

What’s the effect of abnormal RYR receptors?

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17
Q

What are some 3xamp,es of genetic polymorphisms in drugs?

A