Drugs Used In Coagulation Disorders

Question 1

What 2 categories of drugs are used in coagulation?

Answer 1

1. Drugs used to reduce clotting
2. Drugs used in bleeding disorders

Question 2

What drugs are used to reduce clotting?

Answer 2

Question 3

What are platelet aggregation inhibitors?

Answer 3

Question 4

What are the categories of platelet aggregation inhibitors?

Answer 4

Question 5

How does aspirin inhibit COX?

Answer 5

Question 6

What is fibrinogen?

Answer 6

Question 7

What are the uses of aspirin?

Answer 7

Question 8

What are the ADP receptor blockers?

Answer 8

Question 9

How do Ticagrelor and cangrelor work?

Answer 9

Question 10

Describe the pharmacogenetics of Clopudogrel

Answer 10

Question 11

Describe the drug interactions of Clopidogrel

Answer 11

Question 12

How is Prasugrel activated?

Answer 12

Question 13

What are the MOA of ADP receptor blockers?

Answer 13

Question 14

What are the uses of ADP receptor blockers?

Answer 14

Question 15

What is Dipyridamole used for?

Answer 15

Question 16

What is cilostazol used for?

Answer 16

Question 17

What’s the purpose of GP IIb/IIIa?

Answer 17

Question 18

What are the GP IIb/IIIa receptor blockers?

Answer 18

Question 19

What are the drugs to reduce clotting?

Answer 19

Question 20

What are the type of anticoagulants?

Answer 20

Question 21

What are the indirect thrombin and factor XA inhibitors?

Answer 21

Question 22

Describe unfractioned & low-molecular weight heparins & fondaparinux

Answer 22

Question 23

What the molecular weight of unfractionated heparin?

Answer 23

Question 24

How are low molecular weight heparins produced?

Answer 24

Question 25

What’s the MOA of heparin?

Answer 25

Question 26

Contrast UFH and LMWH

Answer 26

Question 27

What’s the importance of AT3 to heparin?

Answer 27

Question 28

How do we monitor heparin?

Answer 28

Question 29

Why don’t we need to monitor LMWH?

Answer 29

Question 30

What are the uses of heparin?

Answer 30

Question 31

What are the uses of heparin?

Answer 31

Question 32

What are the adverse effects of heparin?

Answer 32

Question 33

What causes heparin induced thrombocytopenia type II?

Answer 33

Question 34

What is Fondaparinux?

Answer 34

Question 35

How does. Warfarin work?

Answer 35

Question 36

What are the anticoagulant effects of warfarin?

Answer 36

Question 37

How do we monitor warfarin levels?

Answer 37

Question 38

What are the uses of warfarin?

Answer 38

Question 39

How can warfarin cause a hemorrhage?

Answer 39

Question 40

Describe warfarin induced skein necrosis

Answer 40

Question 41

Why isn’t warfarin used in pregnancy?

Answer 41

Question 42

What are the drug interactions of wafrfarin?

Answer 42

Question 43

What are the direct thrombin inhibitors?

Answer 43

Question 44

What are the parental DTIs?

Answer 44

Question 45

What are the oral DTIs?

Answer 45

Question 46

What are the direct factor Xa inhibitors?

Answer 46

Question 47

What are the choices of oral anticoagulant?

Answer 47

Question 48

Describe the management of DVT & PE

Answer 48

Question 49

What are thrombolytics?

Answer 49

Question 50

Contrast fibrin-specific vs non-fibrin specific agents

Answer 50

Question 51

What are the non-fibrin thrombolytics?

Answer 51

Question 52

What are the fibrin-specific thrombolytics ?

Answer 52

Question 53

What are the uses of thrombolytics?

Answer 53

Question 54

What are the drugs used to to treat bleeding?

Answer 54

Question 55

What are the plasminogen activation inhibitors?

Answer 55

Question 56

What is protamine sulfate?

Answer 56

Question 57

Describe warfarin reversal

Answer 57

Question 58

What can factor 8 & 9 deficiency lead to?

Answer 58