Antihyoerlipidemic Drugs Flashcards

1
Q

What is hyperlipidemia?

A
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2
Q

How do3s lipid conc. Affect cardiovascular risk?

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3
Q

What often how can cardiovascular mortality be impacted by diet?

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4
Q

What are the main risk factors of hyperlipidemia?

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5
Q

What are the primary causes of hyperlipidemia?

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6
Q

What are the etiology and classifications of primary hyperlipidemia?

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7
Q

What is type 1 familial hyperchylomicronemia?

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8
Q

What is type 2a familial hypercholesterolemia?

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9
Q

What is the type 2b familial combined hyperlipidemia?

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10
Q

What is the type 3 familial Dysbetalipoproteinemia?

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11
Q

What is type 4 familial hypertriglyceridemia?

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12
Q

What is type 5 mixed hypertriglyceridemia?

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13
Q

What are the causes of secondary hyperlipidemia?

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14
Q

What are the causes of drugs that may increase LDL-C ?

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15
Q

Discuss Pharmological management of hyperlipidemia

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16
Q

Discuss pharmalogical management of hyperlipidemia

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17
Q

What are the anti hyperlipidemic drugs?

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18
Q

What are the main statins ?

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19
Q

What’s the MOA of statins?

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20
Q

How do statins increase LDL clearance?

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21
Q

What’s the most effective drug in lowering LDL?

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22
Q

What are the main effects of statins? Which statins are most effective in reducing TG?

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23
Q

What are the uses of statins?

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24
Q

Who should be treated with statins?

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25
Q

What are the adverse effects of statins?

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26
Q

How do we monitor statins?

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27
Q

What is niacin?

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28
Q

What is the MOA of niacin?

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29
Q

How does niacin affect lipoprotein conc.?

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30
Q

What are the uses of niacin?

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31
Q

What are the adverse effects of niacin?

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32
Q

What are the rare adverse effects of niacin?

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33
Q

What are fibrates?

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34
Q

What is the mechanism of action of fibrates?

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35
Q

What are the uses of fibrates?

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36
Q

What are the adverse effects of fibrates?

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37
Q

What are the drug interactions of fibrates?

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38
Q

What are the bile acid binding resins?

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39
Q

What do bile resins do?

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40
Q

What are the MOA bile acid binding resins?

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41
Q

What are the uses of bile acid binding resins?

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42
Q

What are the adverse effects of bile acid binding resins?

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43
Q

What are the drug interactions of bile acid binding resins?

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44
Q

What is Ezetimibe?

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45
Q

What is the MOA of ezetimbe?

A
46
Q

How does ezetimbe interact with cholesterol?

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47
Q

What are the uses of ezetimbe?

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48
Q

What are the adverse effects of ezetimbe?

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49
Q

What Are the drug interactions of ezetimbe?

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50
Q

What are omega-3 fatty acid esters?

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51
Q

What are PCSK9 inhibitors?

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52
Q

What are the monoclonal antibodies against PCSK9?

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53
Q

What is the MOA of monoclonal antibodies against PCSK9?

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54
Q

What’s the mechanism of action ofPSK9 ?inhibitors bibding action?

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55
Q

What are the uses of monoclonal antibodies against PCSK9?

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56
Q

What are siRNA inhibitors of PCSK9?

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57
Q

What are the effects of anti hyperlipidemias?

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58
Q

When are antihyperlipidemic combinations used?

A
59
Q

When are is drug therapy recommended for each Dyslipidemia?

A
60
Q

Which antihyperlipidemic drugs used in pregnancy?

A